Mitochondrial function is maintained by several strictly coordinated mechanisms, collectively
termed mitochondrial quality control mechanisms, including fusion and fission, degradation …

Programmed cell death (PCD) is a fundamental biological process that plays a critical role in
cell development, differentiation, and homeostasis. The secretion and uptake of extracellular …

Autophagy is a catabolic process in which a double-membrane organelle, the
autophagosome (AP), engulfs cellular components that will be degraded in the lysosomes …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a growing
class of natural products biosynthesized from a genetically encoded precursor peptide. The …

Abstract VPS37A, an ESCRT-I complex component, is required for recruiting a subset of
ESCRT proteins to the phagophore for autophagosome closure. However, the mechanism …

Nearly two decades have passed since the first report on autophagy acting as a cell-
autonomous defense against Mycobacterium tuberculosis. This helped usher a new area of …

Membrane atg8ylation is a homeostatic process responding to membrane remodeling and
stress signals. Membranes are atg8ylated by mammalian ATG8 ubiquitin-like proteins …