MicroRNA regulation of RNA virus replication and pathogenesis

DW Trobaugh, WB Klimstra - Trends in molecular medicine, 2017 - cell.com
microRNAs (miRNAs) are non-coding RNAs that regulate many processes within a cell by
manipulating protein levels through direct binding to mRNA and influencing translation …

Dengue virus infection: a tale of viral exploitations and host responses

N Nanaware, A Banerjee, S Mullick Bagchi, P Bagchi… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …

Innate and adaptive immune evasion by dengue virus

MF Lee, GZ Voon, HX Lim, ML Chua… - Frontiers in Cellular and …, 2022 - frontiersin.org
Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …

Melatonin alleviates radiation‐induced lung injury via regulation of miR‐30e/NLRP3 Axis

X Wu, H Ji, Y Wang, C Gu, W Gu… - Oxidative medicine and …, 2019 - Wiley Online Library
Melatonin is a well‐known anti‐inflammatory and antioxidant molecule, which plays a
crucial role in various physiological functions. In this study, mice received a single dose of …

Role of microRNAs in antiviral responses to dengue infection

RR Wong, N Abd-Aziz, S Affendi, CL Poh - Journal of biomedical science, 2020 - Springer
Dengue virus (DENV) is the etiological agent of dengue fever. Severe dengue could be fatal
and there is currently no effective antiviral agent or vaccine. The only licensed vaccine …

The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection

B Hazra, KL Kumawat, A Basu - Science signaling, 2017 - science.org
Effective recognition of viral components and the subsequent stimulation of the production of
type I interferons (IFNs) is crucial for the induction of host antiviral immunity. The failure of …

Complex interaction between dengue virus replication and expression of miRNA-133a

JA Castillo, JC Castrillón, M Diosa-Toro… - BMC infectious …, 2015 - Springer
Background Dengue virus (DENV) is the most common vector-borne viral infection
worldwide with approximately 390 million cases and 25,000 reported deaths each year …

MicroRNA and mRNA dysregulation in astrocytes infected with Zika virus

RA Kozak, A Majer, MJ Biondi, SJ Medina, LW Goneau… - Viruses, 2017 - mdpi.com
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus
reported to be associated with microcephaly, and recent work in animal models …

Cellular microRNA-miR-548g-3p modulates the replication of dengue virus

W Wen, Z He, Q Jing, Y Hu, C Lin, R Zhou, X Wang… - Journal of Infection, 2015 - Elsevier
Objective It has been well recognized that microRNA plays a role in the host–pathogen
interaction network. The significance of microRNA in the regulation of dengue virus (DENV) …

Zika virus antagonizes interferon response in patients and disrupts RIG-I–MAVS interaction through its CARD-TM domains

Y Hu, X Dong, Z He, Y Wu, S Zhang, J Lin, Y Yang… - Cell & bioscience, 2019 - Springer
Background The emerging threat to global health associated with the Zika virus (ZIKV)
epidemics and its link to severe complications highlights a growing need to better …