Key transcription factors in the differentiation of mesenchymal stem cells

SG Almalki, DK Agrawal - Differentiation, 2016 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells that represent a promising source for
regenerative medicine. MSCs are capable of osteogenic, chondrogenic, adipogenic and …

Spheroid culture of mesenchymal stem cells

Z Cesarz, K Tamama - Stem cells international, 2016 - Wiley Online Library
Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …

A human epidermal growth factor-curcumin bandage bioconjugate loaded with mesenchymal stem cell for in vivo diabetic wound healing

C Mohanty, J Pradhan - Materials Science and Engineering: C, 2020 - Elsevier
Bone-marrow-derived mesenchymal stem cells (MSCs) are of growing interest for the
treatment of diabetic wound healing. However, they are often associated with poor …

Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds

PS Couto, MC Rotondi, A Bersenev, CJ Hewitt… - Biotechnology …, 2020 - Elsevier
Human mesenchymal stem/stromal cells (hMSCs) present a key therapeutic cellular
intervention for use in cell and gene therapy (CGT) applications due to their …

Human mesenchymal stem cells cultured on silk hydrogels with variable stiffness and growth factor differentiate into mature smooth muscle cell phenotype

M Floren, W Bonani, A Dharmarajan, A Motta… - Acta biomaterialia, 2016 - Elsevier
Cell-matrix and cell-biomolecule interactions play critical roles in a diversity of biological
events including cell adhesion, growth, differentiation, and apoptosis. Evidence suggests …

Epidermal growth factor (EGF) treatment on multipotential stromal cells (MSCs). Possible enhancement of therapeutic potential of MSC

K Tamama, H Kawasaki, A Wells - BioMed Research …, 2010 - Wiley Online Library
Adult bone marrow multipotential stromal cells (MSCs) hold great promise in regenerative
medicine and tissue engineering. However, due to their low numbers upon harvesting …

Mechanobiological conditioning of mesenchymal stem cells for enhanced vascular regeneration

J Lee, K Henderson, MW Massidda… - Nature biomedical …, 2021 - nature.com
Using endogenous mesenchymal stem cells for treating myocardial infarction and other
cardiovascular conditions typically results in poor efficacy, in part owing to the heterogeneity …

Novel applications of mesenchymal stem cell-derived exosomes for myocardial infarction therapeutics

SJ Ozaki Tan, JF Floriano, L Nicastro, C Emanueli… - Biomolecules, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity globally,
representing approximately a third of all deaths every year. The greater part of these cases …

Differentiation of human bone marrow mesenchymal stem cells into bladder cells: potential for urological tissue engineering

H Tian, S Bharadwaj, Y Liu, PX Ma, A Atala… - … Engineering Part A, 2010 - liebertpub.com
Bone marrow mesenchymal stem cells (BMSCs) are capable of differentiating into multiple
cell types, providing an alternative cell source for cell-based therapy and tissue engineering …

Building gut from scratch—progress and update of intestinal tissue engineering

L Tullie, BC Jones, P De Coppi, VSW Li - … Reviews Gastroenterology & …, 2022 - nature.com
Short bowel syndrome (SBS), a condition defined by insufficient absorptive intestinal
epithelium, is a rare disease, with an estimated prevalence up to 0.4 in 10,000 people …