Noncoding RNA therapeutics—challenges and potential solutions
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Novel nanomedicines to overcome cancer multidrug resistance
Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …
[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
Nanoparticles: From synthesis to applications and beyond
A Selmani, D Kovačević, K Bohinc - Advances in colloid and interface …, 2022 - Elsevier
In modern-day research, nanoparticles (size< 100 nm) are an indispensable tool for various
applications, especially in the field of biomedicine. Although enormous efforts have been …
applications, especially in the field of biomedicine. Although enormous efforts have been …
Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy
X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive Materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …
various fields due to a wide range of treatments applications, as demonstrated in preclinical …
Drug delivery of natural products through nanocarriers for effective breast cancer therapy: A comprehensive review of literature
Despite recent advances in the diagnosis and treatment of breast cancer (BC), it remains a
global health issue affecting millions of women annually. Poor prognosis in BC patients is …
global health issue affecting millions of women annually. Poor prognosis in BC patients is …
The progress and perspective of strategies to improve tumor penetration of nanomedicines
J Hu, X Yuan, F Wang, H Gao, X Liu, W Zhang - Chinese Chemical Letters, 2021 - Elsevier
Tumor penetration is important for effectively tumor targeting drug delivery. Recently, many
researches are published to overcome the barriers that restrict tumor penetration and …
researches are published to overcome the barriers that restrict tumor penetration and …
[HTML][HTML] Gene therapy in cancer treatment: why go nano?
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …
development of novel approaches and strategies to fight this disease, but the efficacy of the …
Nanoparticle drug delivery systems for synergistic delivery of tumor therapy
D Chen, X Liu, X Lu, J Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …