Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies

H Christou, RA Khalil - American Journal of Physiology …, 2022 - journals.physiology.org
Pulmonary hypertension (PH) is a serious disease characterized by various degrees of
pulmonary vasoconstriction and progressive fibroproliferative remodeling and inflammation …

[HTML][HTML] A peripheral system disease—Pulmonary hypertension

Y Sun, C Chen, Q Yan, S Wang, Y Tan, J Long… - Biomedicine & …, 2024 - Elsevier
Pulmonary hypertension (PH) is a cardiovascular disorder characterized by substantial
morbidity and mortality rates. It is a chronic condition characterized by intricate pathogenesis …

[HTML][HTML] The combined use of acetazolamide and Rhodiola in the prevention and treatment of altitude sickness

C Cao, H Zhang, Y Huang, Y Mao, L Ma… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Altitude sickness (AS), which is caused by rapid exposure to low amounts of
oxygen at high elevations, poses a great threat to humans working and traveling in these …

[HTML][HTML] Effect of 5 weeks of oral acetazolamide on patients with pulmonary vascular disease: a randomized, double-blind, cross-over trial

M Lichtblau, S Saxer, J Müller, P Appenzeller, C Berlier… - Pulmonology, 2024 - Elsevier
Background The carbonic anhydrase inhibitor acetazolamide stimulates ventilation through
metabolic acidosis mediated by renal bicarbonate excretion. In animal models …

The Role of Sex in the Effects of Smoking and Nicotine in Cardiovascular Function, Atherosclerosis, and Inflammation

G Salazar, AM Centner, AE Cullen, L Khalili… - bioRxiv, 2024 - biorxiv.org
Cigarette smoke (CS) invokes an inflammatory response involving increased levels of
circulating cytokines and chemokines, vascular dysfunction, and atherosclerosis. The role of …