Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release
A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …
delivery method of drugs that are poorly soluble in water. The investigations carried out have …
[HTML][HTML] Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …
innovative nanoscale particulate materials, are being concurrently prepared by the quality …
[HTML][HTML] Application of smart solid lipid nanoparticles to enhance the efficacy of 5-fluorouracil in the treatment of colorectal cancer
Fluorouracil (5-FU) is a standard treatment option for colorectal cancer (CRC) but its rapid
metabolism and systemic instability (short half-life) has hindered its therapeutic efficacy. The …
metabolism and systemic instability (short half-life) has hindered its therapeutic efficacy. The …
[HTML][HTML] Optimization of the conditions of solid lipid nanoparticles (SLN) synthesis
E Musielak, A Feliczak-Guzik, I Nowak - Molecules, 2022 - mdpi.com
Solid lipid nanoparticles (SLNs) have been synthesized as potential drug delivery systems.
They are classified as solid lipid nanocarriers that can successfully carry both hydrophilic …
They are classified as solid lipid nanocarriers that can successfully carry both hydrophilic …
Statistically designed dexibuprofen loaded solid lipid nanoparticles for enhanced oral bioavailability
Abstract Dexibuprofen (DBPN), a non-steroidal anti-inflammatory drug (NSAID), exhibit its
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
Development and characterization of nanostructured lipid carrier-based gels for the transdermal delivery of donepezil
IT Mendes, ALM Ruela, FC Carvalho, JTJ Freitas… - Colloids and Surfaces B …, 2019 - Elsevier
Donepezil is one of the main compounds used in the therapy of Alzheimer's disease. Oral
administration of this drug presents many drawbacks, resulting in treatment non-adherence …
administration of this drug presents many drawbacks, resulting in treatment non-adherence …
Hybrid lipid–nanoparticle complexes for biomedical applications
Biomolecule–nanoparticle hybrids have proven to be one of most promising frontiers in
biomedical research. In recent years, there has been an increased focus on the …
biomedical research. In recent years, there has been an increased focus on the …
Tadpole-Like Anisotropic Polymer/Lipid Janus Nanoparticles for Nose-to-Brain Drug Delivery: Importance of Geometry, Elasticity on Mucus-Penetration Ability
B Okmen Altas, GD Kalaycioglu… - Molecular …, 2024 - ACS Publications
Asymmetric geometry (aspect ratio> 1), moderate stiffness (ie, semielasticity), large surface
area, and low mucoadhesion of nanoparticles are the main features to reach the brain by …
area, and low mucoadhesion of nanoparticles are the main features to reach the brain by …
On the structure of solid lipid nanoparticles
Solid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial
surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their …
surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their …
Optimization of linalool-loaded solid lipid nanoparticles using experimental factorial design and long-term stability studies with a new centrifugal sedimentation …
Abstract Linalool (C 10 H 18 O), also known as 3, 7-dimethyl-1, 6-octadien-3-ol, is the most
common acyclic monoterpene tertiary alcohol present in essential oils of several aromatic …
common acyclic monoterpene tertiary alcohol present in essential oils of several aromatic …