Pyrazoline hybrids as promising anticancer agents: An up-to-date overview

D Matiadis, M Sagnou - International Journal of Molecular Sciences, 2020 - mdpi.com
Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship

Z Peng, G Wang, QH Zeng, Y Li, H Liu… - Critical Reviews in …, 2022 - Taylor & Francis
Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …

In vitro and in silico studies of fluorinated 2, 3‐disubstituted thiazolidinone‐pyrazoles as potential α‐amylase inhibitors and antioxidant agents

D Ganavi, R Ramu, V Kumar, SM Patil… - Archiv der …, 2022 - Wiley Online Library
As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …

An efficient ultrasound-assisted CH3COONa catalyzed synthesis of thiazolidinone molecule: theoretical and nonlinear optical evaluations of thiazolidinone-Schiff base …

JK Salim, QMA Hassan, AM Jassem, HA Sultan… - Optical Materials, 2022 - Elsevier
Chemical synthesis, structural analysis, theoretical calculations and optical properties
exploration of (E)-2-((E)-(4-nitrobenzylidene) hydrazono)-3-phenyl-4-thiazolidinone 7 (C 16 …

Choline chloride-based DES as solvents/catalysts/chemical donors in pharmaceutical synthesis

R Amoroso, F Hollmann, C Maccallini - Molecules, 2021 - mdpi.com
DES are mixtures of two or more compounds, able to form liquids upon mixing, with lower
freezing points when compared to the individual constituents (eutectic mixtures). This …

A comprehensive survey upon diverse and prolific applications of chitosan-based catalytic systems in one-pot multi-component synthesis of heterocyclic rings

H Mousavi - International Journal of Biological Macromolecules, 2021 - Elsevier
Heterocyclic compounds are among the most prestigious and valuable chemical molecules
with diverse and magnificent applications in various sciences. Due to the remarkable and …

Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches

KM Dawood, MA Raslan, AA Abbas… - Frontiers in …, 2021 - frontiersin.org
A series of bis-thiazoles 5a–g were synthesized from bis-thiosemicarbazone 3 with
hydrazonoyl chlorides 4a–g. Reaction of 3 with two equivalents of α-halocarbonyl …

Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition

MS Nafie, SM Kishk, S Mahgoub… - Chemical Biology & …, 2022 - Wiley Online Library
Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …

Boosting the antimicrobial performance based on new fused spirothiazolidine framework analogs

WI El-Sofany, EM Flefel, OM Darwesh… - Journal of the Iranian …, 2022 - Springer
Abstract New spiro [cyclohexane-1, 2'-thiazolo [4, 5-b] pyridine derivatives (3–23) were
investigated. Then there is in vitro antimicrobial potency against possible organisms …

[HTML][HTML] New 4-thiazolidinone-based molecules Les-2769 and Les-3266 as possible PPARγ modulators

M Bar, B Skóra, A Tabęcka-Łonczyńska, S Holota… - Bioorganic …, 2022 - Elsevier
Abstract Development of cancer drug-resistance is still an ongoing problem in the modern
anticancer treatment. Therefore, there is a need to search for a new active substance, which …