Human papillomavirus testing in the prevention of cervical cancer

M Schiffman, N Wentzensen… - Journal of the …, 2011 - academic.oup.com
Strong evidence now supports the adoption of cervical cancer prevention strategies that
explicitly focus on persistent infection with the causal agent, human papillomavirus (HPV) …

Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions

RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

[HTML][HTML] Association between cervical microbiota and HPV: could this be the key to complete cervical cancer eradication?

E Cascardi, G Cazzato, A Daniele, E Silvestris… - Biology, 2022 - mdpi.com
Simple Summary The microbiota can modulate immune responses and modify the
physiology of the human organism, thereby increasing infective risks and a neoplastic …

Human papillomavirus infection and the multistage carcinogenesis of cervical cancer

M Schiffman, N Wentzensen - Cancer epidemiology, biomarkers & …, 2013 - AACR
This short review outlines our understanding of cervical cancer precursors, concentrating on
the central etiologic role of persistent human papillomavirus infection. The stages of cervical …

[HTML][HTML] A review of methods for detect human Papillomavirusinfection

ALP Abreu, RP Souza, F Gimenes, MEL Consolaro - Virology journal, 2012 - Springer
Human Papillomavirus (HPV) is the most common sexually transmitted virus. Worldwide, the
most common high-risk (HR)-HPV are-16/18, and approximately 70% of cervical cancers …

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

JA Den Boon, D Pyeon, SS Wang… - Proceedings of the …, 2015 - National Acad Sciences
To study the multistep process of cervical cancer development, we analyzed 128 frozen
cervical samples spanning normalcy, increasingly severe cervical intraepithelial neoplasia …

Human papillomavirus and diseases of the upper airway: head and neck cancer and respiratory papillomatosis

ML Gillison, L Alemany, PJF Snijders, A Chaturvedi… - Vaccine, 2012 - Elsevier
Human papillomavirus (HPV) infection is causally associated with benign and malignant
diseases of the upper airway, including respiratory papillomatosis and oropharyngeal …

Screening for cervical cancer precursors with p16/Ki-67 dual-stained cytology: results of the PALMS study

H Ikenberg, C Bergeron, D Schmidt… - Journal of the …, 2013 - academic.oup.com
Background Pap cytology is known to be more specific but less sensitive than testing for
human papillomavirus (HPV) for the detection of high-grade cervical intraepithelial …

Cervical cancer screening postpandemic: self-sampling opportunities to accelerate the elimination of cervical cancer

T Lozar, R Nagvekar, C Rohrer… - … Journal of Women's …, 2021 - Taylor & Francis
The persisting burden of cervical cancer in underserved populations and low-resource
regions worldwide, worsened by the onset of the COVID-19 pandemic, requires proactive …

Performance of p16/Ki-67 immunostaining to detect cervical cancer precursors in a colposcopy referral population

N Wentzensen, L Schwartz, RE Zuna, K Smith… - Clinical Cancer …, 2012 - AACR
Purpose: Cytology-based screening has limited sensitivity to detect prevalent cervical
precancers. Human papilloma virus (HPV) DNA testing is highly sensitive and provides a …