Same substrate, many reactions: oxygen activation in flavoenzymes
Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Enzymatic halogenation and dehalogenation reactions: pervasive and mechanistically diverse
Naturally produced halogenated compounds are ubiquitous across all domains of life where
they perform a multitude of biological functions and adopt a diversity of chemical structures …
they perform a multitude of biological functions and adopt a diversity of chemical structures …
Biosynthesis of the modified tetrapyrroles—the pigments of life
Modified tetrapyrroles are large macrocyclic compounds, consisting of diverse conjugation
and metal chelation systems and imparting an array of colors to the biological structures that …
and metal chelation systems and imparting an array of colors to the biological structures that …
Cyanobacteria and eukaryotic algae use different chemical variants of vitamin B12
Eukaryotic microalgae and prokaryotic cyanobacteria are the major components of the
phytoplankton. Determining factors that govern growth of these primary producers, and how …
phytoplankton. Determining factors that govern growth of these primary producers, and how …
Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics
The vitamin B12 family of cofactors known as cobamides are essential for a variety of
microbial metabolisms. We used comparative genomics of 11,000 bacterial species to …
microbial metabolisms. We used comparative genomics of 11,000 bacterial species to …
Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers
CA Abbas, AA Sibirny - Microbiology and molecular biology …, 2011 - Am Soc Microbiol
SUMMARY Riboflavin [7, 8-dimethyl-10-(1′-d-ribityl) isoalloxazine, vitamin B2] is an
obligatory component of human and animal diets, as it serves as the precursor of flavin …
obligatory component of human and animal diets, as it serves as the precursor of flavin …
Vitamin B12
The biosynthesis of B 12, involving up to 30 different enzyme-mediated steps, only occurs in
bacteria. Thus, most eukaryotes require an external source of B 12, and yet the vitamin …
bacteria. Thus, most eukaryotes require an external source of B 12, and yet the vitamin …
Microbial production of vitamin B12: a review and future perspectives
H Fang, J Kang, D Zhang - Microbial cell factories, 2017 - Springer
Vitamin B 12 is an essential vitamin that is widely used in medical and food industries.
Vitamin B 12 biosynthesis is confined to few bacteria and archaea, and as such its …
Vitamin B 12 biosynthesis is confined to few bacteria and archaea, and as such its …
Flavoenzymes: versatile catalysts in biosynthetic pathways
CT Walsh, TA Wencewicz - Natural product reports, 2013 - pubs.rsc.org
Covering: up to the end of May 2012 Riboflavin-based coenzymes, tightly bound to enzymes
catalyzing substrate oxidations and reductions, enable an enormous range of chemical …
catalyzing substrate oxidations and reductions, enable an enormous range of chemical …
Reduction of polynitroaromatic compounds: the bacterial nitroreductases
MD Roldán, E Pérez-Reinado, F Castillo… - FEMS microbiology …, 2008 - academic.oup.com
Most nitroaromatic compounds are toxic and mutagenic for living organisms, but some
microorganisms have developed oxidative or reductive pathways to degrade or transform …
microorganisms have developed oxidative or reductive pathways to degrade or transform …