The rapid development of nanotechnology offers a variety of potential therapeutic strategies
for cancer treatment. High atomic element nanomaterials are often utilized as …

The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …

Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Upon DNA damage or other stressors, the tumor suppressor p53 is activated, leading to
transient expression of the cyclin-dependent kinase inhibitor (CKI) p21. This either triggers …

Purpose Reactive oxygen species (ROS) are produced in cancer cells as a result of
increased metabolic rate, dysfunction of mitochondria, elevated cell signaling, expression of …

Risks to health are the prime consideration in all human situations of ionizing radiation
exposure and therefore of relevance to radiation protection in all occupational, medical, and …

Cellular senescence is a stress response mechanism ensuring homeostasis. Its temporal
activation during embryonic development or normal adult life is linked with beneficial …

Biological responses to ionizing radiation (IR) have been studied for many years, generally
showing the dependence of these responses on the quality of radiation, ie, the radiation …

Prostate cancer remains the most frequently diagnosed cancer in men in North America, and
despite recent advances in treatment patients with metastatic disease continue to have poor …

DNA damage plays a causal role in numerous human pathologies including cancer,
premature aging, and chronic inflammatory conditions. In response to genotoxic insults, the …