Macrophage functional diversity in NAFLD—more than inflammation
Macrophages have diverse phenotypes and functions due to differences in their origin,
location and pathophysiological context. Although their main role in the liver has been …
location and pathophysiological context. Although their main role in the liver has been …
Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?
P Rada, Á González-Rodríguez, C García-Monzón… - Cell death & …, 2020 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic …
worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic …
Molecular pathways of nonalcoholic fatty liver disease development and progression
F Bessone, MV Razori, MG Roma - Cellular and Molecular Life Sciences, 2019 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a main hepatic manifestation of metabolic
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …
Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review
Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …
entities sharing common clinical and physio-pathological features, with insulin resistance …
[HTML][HTML] Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”
YL Fang, H Chen, CL Wang, L Liang - World journal of …, 2018 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has become the dominant form of chronic liver
disease in children and adolescents with the increasing prevalence of obesity worldwide …
disease in children and adolescents with the increasing prevalence of obesity worldwide …
The interplay between insulin resistance, inflammation, oxidative stress, base excision repair and metabolic syndrome in nonalcoholic fatty liver disease
S Ziolkowska, A Binienda, M Jabłkowski… - International journal of …, 2021 - mdpi.com
One of the most common chronic liver disorders, affecting mainly people in Western
countries, is nonalcoholic fatty liver disease (NAFLD). Unfortunately, its pathophysiological …
countries, is nonalcoholic fatty liver disease (NAFLD). Unfortunately, its pathophysiological …
[HTML][HTML] Pathogenesis of liver cirrhosis
WC Zhou, QB Zhang, L Qiao - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Liver cirrhosis is the final pathological result of various chronic liver diseases, and fibrosis is
the precursor of cirrhosis. Many types of cells, cytokines and miRNAs are involved in the …
the precursor of cirrhosis. Many types of cells, cytokines and miRNAs are involved in the …
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen… - Archives of …, 2013 - Springer
This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …
Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management
T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …