Tetraspanins are molecular scaffolds that distribute proteins into highly organized
microdomains consisting of adhesion, signaling, and adaptor proteins. Many reports have …

Like most modern molecular biology and natural product chemistry, understanding
cannabinoid pharmacology centers around molecular interactions, in this case, between the …

Melatonin has been detected in plants in 1995; however, the function and signaling pathway
of this putative phytohormone are largely undetermined due to a lack of knowledge about its …

The relationship between corals and dinoflagellates of the genus Symbiodinium is
fundamental to the functioning of coral ecosystems. It has been suggested that reef corals …

Abstract The Receptor for Activated C Kinase 1 (RACK1) is a member of the tryptophan-
aspartate repeat (WD-repeat) family of proteins and shares significant homology to the β …

Epithelial–mesenchymal transition (EMT) is a reversible cellular process, characterized by
changes in gene expression and activation of proteins, favoring the trans-differentiation of …

The G-protein-coupled receptor (GPCR) signaling system is one of the main signaling
pathways in eukaryotes. Here, we analyze the evolutionary history of all its components …

Cells translate extracellular signals to regulate processes such as differentiation,
metabolism and proliferation, via transmembranar receptors. G protein-coupled receptors …

Many different intrinsically disordered proteins and proteins with intrinsically disordered
regions are associated with neurodegenerative diseases. These types of proteins including …

UBR box E3 ligases, also called N-recognins, are integral components of the N-degron
pathway. Representative N-recognins include UBR1, UBR2, UBR4, and UBR5, and they …