Escherichia coli are remarkably versatile microorganisms and important members of the
normal intestinal microbiota of humans and animals. This harmless commensal organism …

Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …

Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive
approach for pathogen detection. The cost of high-throughput or next-generation …

Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …

This review provides a state-of-the-art description of the performance of Sanger cycle
sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical …

Advancement of DNA sequencing technology allows the routine use of genome sequences
in the various fields of microbiology. The information held in genome sequences proved to …

The gold standard for clinical diagnosis of bacterial lower respiratory infections (LRIs) is
culture, which has poor sensitivity and is too slow to guide early, targeted antimicrobial …

Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

The testing and rapid detection of pathogenic organisms is a crucial protocol in the
prevention and identification of crises related to health, safety and wellbeing. Pathogen …

Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …