Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Top-down regulation of motivated behaviors via lateral septum sub-circuits

A Besnard, F Leroy - Molecular psychiatry, 2022 - nature.com
How does cognition regulate innate behaviors? While the cognitive functions of the cortex
have been extensively studied, we know much less about how cognition can regulate innate …

[HTML][HTML] The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation

CR Lee, A Chen, KM Tye - Cell, 2021 - cell.com
Social homeostasis is the ability of individuals to detect the quantity and quality of social
contact, compare it to an established set-point in a command center, and adjust the effort …

Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice

MT Birnie, AK Short, GB de Carvalho… - Nature …, 2023 - nature.com
Disrupted operations of the reward circuit underlie major emotional disorders, including
depression, which commonly arise following early life stress/adversity (ELA). However, how …

Neural mechanisms of social homeostasis

GA Matthews, KM Tye - Annals of the New York Academy of …, 2019 - Wiley Online Library
Social connections are vital to survival throughout the animal kingdom and are dynamic
across the life span. There are debilitating consequences of social isolation and loneliness …

A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors

H Wang, T Qian, Y Zhao, Y Zhuo, C Wu, T Osakada… - Science, 2023 - science.org
Neuropeptides are key signaling molecules in the endocrine and nervous systems that
regulate many critical physiological processes. Understanding the functions of …

The hypothalamus for whole-body physiology: from metabolism to aging

T Liu, Y Xu, CX Yi, Q Tong, D Cai - Protein & Cell, 2022 - academic.oup.com
Obesity and aging are two important epidemic factors for metabolic syndrome and many
other health issues, which contribute to devastating diseases such as cardiovascular …

Toward a structural understanding of class B GPCR peptide binding and activation

YL Liang, MJ Belousoff, P Zhao, C Koole, MM Fletcher… - Molecular cell, 2020 - cell.com
Class BG protein-coupled receptors (GPCRs) are important therapeutic targets for major
diseases. Here, we present structures of peptide and Gs-bound pituitary adenylate cyclase …

[图书][B] Applied animal endocrinology

EJ Squires - 2024 - cabidigitallibrary.org
This book explains the role of hormones in improving and monitoring the production,
performance, reproduction, behaviour and health of livestock animals, focusing on cattle …

Pathophysiological implications of neuroinflammation mediated HPA axis dysregulation in the prognosis of cancer and depression

MH Ahmad, MA Rizvi, M Fatima, AC Mondal - Molecular and Cellular …, 2021 - Elsevier
Cancer patients are more likely to develop depressive symptoms and show a poor
prognosis compared to the normal healthy individuals. Cancer occurrence and the …