Cystathionine-β-synthase: molecular regulation and pharmacological inhibition
Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
Metallodendrimers as a promising tool in the biomedical field: An overview
NS del Olmo, R Carloni, P Ortega… - Advances in …, 2020 - Elsevier
Metallodendrimers have emerged in recent years as promising strategies in biomedicine.
These molecules of nanometric size have attracted widespread attention, combining, in a …
These molecules of nanometric size have attracted widespread attention, combining, in a …
Synthesis, characterization of Schiff base metal complexes with 1, 3 propanediamine as secondary chelates and their DNA binding, DNA cleavage, cytotoxicity …
M Pichandi, S Shanmugam - Journal of Molecular Structure, 2024 - Elsevier
A series of Cu (II), Co (II), Ni (II), and Zn (II) complexes were synthesised from ternary Schiff
base ligand (ts) and 1, 3-propanediamine (pda). These complexes were characterised using …
base ligand (ts) and 1, 3-propanediamine (pda). These complexes were characterised using …
Self-assembled ruthenium (II) metallacycles and metallacages with imidazole-based ligands and their in vitro anticancer activity
Y Zhao, L Zhang, X Li, Y Shi, R Ding… - Proceedings of the …, 2019 - National Acad Sciences
Six tetranuclear rectangular metallacycles were synthesized via the [2+ 2] coordination-
driven self-assembly of imidazole-based ditopic donor 1, 4-bis (imidazole-1-yl) benzene and …
driven self-assembly of imidazole-based ditopic donor 1, 4-bis (imidazole-1-yl) benzene and …
Synthesis, structural, and photophysical properties of pyrazolyl bis (pentafluorophenyl) boron complexes
Luminescent materials have garnered significant research interest due to their potential
applications in optoelectronics, sensing, and medical diagnostics. Within this context, tetra …
applications in optoelectronics, sensing, and medical diagnostics. Within this context, tetra …
Induction of apoptosis and autophagy by ternary copper complex towards breast cancer cells
ZY Lee, CH Leong, KUL Lim, C Wong… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: Copper complex has been gaining much attention in anticancer research as a
targeted agent since cancer cells uptake more copper than non-cancerous cells. Our group …
targeted agent since cancer cells uptake more copper than non-cancerous cells. Our group …
Supramolecular assemblies involving unconventional non-covalent contacts in pyrazole-based coordination compounds of Co (II) and Cu (II) pyridinedicarboxylates …
Two coordination compounds of Co (II) and Cu (II) viz.[Co (2, 6-PDC)(Hdmpz) 3]· H 2 O (1)
and [Cu (2, 6-PDC)(Hdmpz) 2](2)(2, 6-PDC= 2, 6-pyridinedicarboxylate, Hdmpz= 3, 5 …
and [Cu (2, 6-PDC)(Hdmpz) 2](2)(2, 6-PDC= 2, 6-pyridinedicarboxylate, Hdmpz= 3, 5 …
Ternary copper (Ii) complex induced apoptosis and cell cycle arrest in colorectal cancer cells
S Arikrishnan, JS Loh, XW Teo… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: The lack of specificity, severe side effects, and development of drug resistance
have largely limited the use of platinum-based compounds in cancer treatment. Therefore …
have largely limited the use of platinum-based compounds in cancer treatment. Therefore …
The role of cystathionine β-synthase in cancer
YW Wang, T Chu, XL Wang, YQ Fan, L Cao, YH Chen… - Cellular …, 2024 - Elsevier
Cystathionine β-synthase (CBS) occupies a key position as the initiating and rate-limiting
enzyme in the sulfur transfer pathway and plays a vital role in health and disease. CBS is …
enzyme in the sulfur transfer pathway and plays a vital role in health and disease. CBS is …
Evaluation of antiproliferative palladium (II) complexes of synthetic bisdemethoxycurcumin towards in vitro cytotoxicity and molecular docking on DNA sequence
N Miklášová, P Herich, JC Dávila-Becerril… - Molecules, 2021 - mdpi.com
Metallodrugs form a large family of therapeutic agents against cancer, among which is
cisplatin, a paradigmatic member. Therapeutic resistance and undesired side effects to Pt (II) …
cisplatin, a paradigmatic member. Therapeutic resistance and undesired side effects to Pt (II) …