Methods to mechanically perturb and characterize GUV-based minimal cell models

NH Wubshet, AP Liu - Computational and Structural Biotechnology Journal, 2023 - Elsevier
Cells shield organelles and the cytosol via an active boundary predominantly made of
phospholipids and membrane proteins, yet allowing communication between the …

[HTML][HTML] Extreme environments and human health: From the immune microenvironments to immune cells

C Pan, Y Zhang, J Yan, Y Zhou, S Wang, X Liu… - Environmental …, 2023 - Elsevier
Exposure to extreme environments causes specific acute and chronic physiological
responses in humans. The adaptation and the physiological processes under extreme …

Cellular mechanotransduction of human osteoblasts in microgravity

NH Wubshet, G Cai, SJ Chen, M Sullivan, M Reeves… - npj …, 2024 - nature.com
Astronauts experience significant and rapid bone loss as a result of an extended stay in
space, making the International Space Station (ISS) the perfect laboratory for studying …

MRTF may be the missing link in a multiscale mechanobiology approach toward macrophage dysfunction in space

R An - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Macrophages exhibit impaired phagocytosis, adhesion, migration, and cytokine production
in space, hindering their ability to elicit immune responses. Considering that the combined …

High-precision ground simulator for laser tracking of gravity satellite

M Zhao, W Hong, C Xiao, Y Ma, Y Bai… - Review of Scientific …, 2024 - pubs.aip.org
Inter-satellite laser ranging is a key technology to improve the measurement precision of
gravity satellites in future missions. However, it requires a stable laser link between …

Mechanophenotyping Actin Networks in Minimal Cell Models

N Wubshet - 2023 - deepblue.lib.umich.edu
Actin, a highly conserved and abundant protein, constructs a fibrous matrix via actin binding
proteins (ABPs) equipping the cell to sustain, exert, and sense forces. Actin assembly plays …