Building tissues from scratch to explore entirely new cell configurations could revolutionize
fundamental understanding in biology. Bioprinting is an emerging technology to do this …

The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Plasticity of cancer invasion and metastasis depends on the ability of cancer cells to switch
between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell …

Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

During development, both cells and tissues must acquire the correct shape to allow their
proper function. This is especially relevant in the nervous system, where the shape of …

The enteric nervous system (ENS) is comprised of a network of neurons and glial cells that
are responsible for coordinating many aspects of gastrointestinal (GI) function. These cells …

Hyaluronan and versican are extracellular matrix (ECM) components that are enriched in the
provisional matrices that form during the early stages of development and disease. These …

Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Contact inhibition of locomotion (CIL) is a process whereby a cell ceases motility or changes
its trajectory upon collision with another cell. CIL was initially characterized more than half a …