The role of IL-6 in cancer cell invasiveness and metastasis—overview and therapeutic opportunities
M Rašková, L Lacina, Z Kejík, A Venhauerová… - Cells, 2022 - mdpi.com
Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various
homeostatic and pathological processes. These activities range from regulating embryonic …
homeostatic and pathological processes. These activities range from regulating embryonic …
[HTML][HTML] Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
E Ku, L Del Vecchio, KU Eckardt, VH Haase… - Kidney international, 2023 - Elsevier
Anemia is common in patients with chronic kidney disease and is associated with a high
burden of morbidity and adverse clinical outcomes. In 2012, Kidney Disease: Improving …
burden of morbidity and adverse clinical outcomes. In 2012, Kidney Disease: Improving …
Strategies to reverse hypoxic tumor microenvironment for enhanced sonodynamic therapy
J Li, Z Yue, M Tang, W Wang, Y Sun… - Advanced Healthcare …, 2024 - Wiley Online Library
Sonodynamic therapy (SDT) has emerged as a highly effective modality for the treatment of
malignant tumors owing to its powerful penetration ability, noninvasiveness, site‐confined …
malignant tumors owing to its powerful penetration ability, noninvasiveness, site‐confined …
The interactions of docetaxel with tumor microenvironment
R Gupta, MM Kadhim, AT Jalil, MQ Alasheqi… - International …, 2023 - Elsevier
There are several interactions within the tumor microenvironment (TME) that affect the
response of cancer cells to therapy. There are also a large number of cells and secretions in …
response of cancer cells to therapy. There are also a large number of cells and secretions in …
Ubiquitination-proteasome system (UPS) and autophagy two main protein degradation machineries in response to cell stress
Y Li, S Li, H Wu - Cells, 2022 - mdpi.com
In response to environmental stimuli, cells make a series of adaptive changes to combat the
injury, repair the damage, and increase the tolerance to the stress. However, once the …
injury, repair the damage, and increase the tolerance to the stress. However, once the …
[HTML][HTML] Quercetin potential effects against SARS‐CoV‐2 infection and COVID‐19‐associated cancer progression by inhibiting mTOR and hypoxia‐inducible factor …
H Zalpoor, M Bakhtiyari, M Liaghat… - Phytotherapy …, 2022 - ncbi.nlm.nih.gov
Dear Editor, Globally, the coronavirus disease-2019 (COVID-19) pandemic has spread
rapidly, with millions of confirmed cases. Severe acute respiratory syndrome coronavirus 2 …
rapidly, with millions of confirmed cases. Severe acute respiratory syndrome coronavirus 2 …
Hypoxia: syndicating triple negative breast cancer against various therapeutic regimens
N Srivastava, SS Usmani, R Subbarayan… - Frontiers in …, 2023 - frontiersin.org
Triple-negative breast cancer (TNBC) is one of the deadliest subtypes of breast cancer (BC)
for its high aggressiveness, heterogeneity, and hypoxic nature. Based on biological and …
for its high aggressiveness, heterogeneity, and hypoxic nature. Based on biological and …
A “One Arrow Three Eagle” Strategy to Improve CM‐272 Primed Bladder Cancer Immunotherapy
R Liu, J Yang, Y Du, X Yu, Y Liao, B Wang… - Advanced …, 2024 - Wiley Online Library
Immunotherapy using an immune‐checkpoint blockade has significantly improved its
therapeutic effects. CM‐272, which is a novel epigenetic inhibitor of G9a, induces …
therapeutic effects. CM‐272, which is a novel epigenetic inhibitor of G9a, induces …
ESM1 enhances fatty acid synthesis and vascular mimicry in ovarian cancer by utilizing the PKM2-dependent warburg effect within the hypoxic tumor …
J Zhang, F Ouyang, A Gao, T Zeng, M Li, H Li, W Zhou… - Molecular Cancer, 2024 - Springer
Background The hypoxic tumor microenvironment is a key factor that promotes metabolic
reprogramming and vascular mimicry (VM) in ovarian cancer (OC) patients. ESM1, a …
reprogramming and vascular mimicry (VM) in ovarian cancer (OC) patients. ESM1, a …
The roles of glycolysis in osteosarcoma
Z Feng, Y Ou, L Hao - Frontiers in Pharmacology, 2022 - frontiersin.org
Metabolic reprogramming is of great significance in the progression of various cancers and
is critical for cancer progression, diagnosis, and treatment. Cellular metabolic pathways …
is critical for cancer progression, diagnosis, and treatment. Cellular metabolic pathways …