Zinc transporter 3 (ZnT3) and vesicular zinc in central nervous system function
BB McAllister, RH Dyck - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Abstract Zinc transporter 3 (ZnT3) is the sole mechanism responsible for concentrating zinc
ions within synaptic vesicles in a subset of the brain's glutamatergic neurons. This vesicular …
ions within synaptic vesicles in a subset of the brain's glutamatergic neurons. This vesicular …
The GABAergic hypothesis for cognitive disabilities in down syndrome
A Contestabile, S Magara, L Cancedda - Frontiers in cellular …, 2017 - frontiersin.org
Down syndrome (DS) is a genetic disorder caused by the presence of a third copy of
chromosome 21. DS affects multiple organs, but it invariably results in altered brain …
chromosome 21. DS affects multiple organs, but it invariably results in altered brain …
[HTML][HTML] Delayed coupling to feedback inhibition during a critical period for the integration of adult-born granule cells
Developing granule cells (GCs) of the adult dentate gyrus undergo a critical period of
enhanced activity and synaptic plasticity before becoming mature. The impact of developing …
enhanced activity and synaptic plasticity before becoming mature. The impact of developing …
Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice
The hippocampus is the brain's center for episodic memories. Its subregions, the dentate
gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal …
gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal …
On how the dentate gyrus contributes to memory discrimination
MT van Dijk, AA Fenton - Neuron, 2018 - cell.com
The dentate gyrus (DG) is crucial for behaviorally discriminating similar spatial memories,
predicting that DG place cells change (" remap") their relative spatial tuning (" place fields") …
predicting that DG place cells change (" remap") their relative spatial tuning (" place fields") …
Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus?
In the adult mammalian brain, newly generated neurons are continuously incorporated into
two networks: interneurons born in the subventricular zone migrate to the olfactory bulb …
two networks: interneurons born in the subventricular zone migrate to the olfactory bulb …
Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever!
During brain development, there is a progressive reduction of intracellular chloride
associated with a shift in GABA polarity: GABA depolarizes and occasionally excites …
associated with a shift in GABA polarity: GABA depolarizes and occasionally excites …
A single dose of 5-MeO-DMT stimulates cell proliferation, neuronal survivability, morphological and functional changes in adult mice ventral dentate gyrus
The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which
neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in …
neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in …
Distinct determinants of sparse activation during granule cell maturation
Adult neurogenesis continually produces a small population of immature granule cells (GCs)
within the dentate gyrus. The physiological properties of immature GCs distinguish them …
within the dentate gyrus. The physiological properties of immature GCs distinguish them …
Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats
The hippocampus plays a key role in learning and memory. Previous studies suggested that
the main types of principal neurons, dentate gyrus granule cells (GCs), CA3 pyramidal …
the main types of principal neurons, dentate gyrus granule cells (GCs), CA3 pyramidal …