Polygenic adaptation: a unifying framework to understand positive selection

N Barghi, J Hermisson, C Schlötterer - Nature Reviews Genetics, 2020 - nature.com
Most adaption processes have a polygenic genetic basis, but even with the recent explosive
growth of genomic data we are still lacking a unified framework describing the dynamics of …

The importance of genomic variation for biodiversity, ecosystems and people

M Stange, RDH Barrett, AP Hendry - Nature Reviews Genetics, 2021 - nature.com
Abstract The 2019 United Nations Global assessment report on biodiversity and ecosystem
services estimated that approximately 1 million species are at risk of extinction. This …

Prospects and limitations of genomic offset in conservation management

C Rellstab, B Dauphin… - Evolutionary …, 2021 - Wiley Online Library
In nature conservation, there is keen interest in predicting how populations will respond to
environmental changes such as climate change. These predictions can help determine …

Polygenic adaptation: From sweeps to subtle frequency shifts

I Höllinger, PS Pennings, J Hermisson - PLoS genetics, 2019 - journals.plos.org
Evolutionary theory has produced two conflicting paradigms for the adaptation of a
polygenic trait. While population genetics views adaptation as a sequence of selective …

The peril of gene-targeted conservation

M Kardos, ABA Shafer - Trends in ecology & evolution, 2018 - cell.com
The genomics revolution has sparked interest in using our increased understanding of the
loci involved in phenotypic variation and adaptation to advance the conservation of …

Predicting thermal adaptation by looking into populations' genomic past

AJ Cortés, F López-Hernández… - Frontiers in …, 2020 - frontiersin.org
Molecular evolution offers an insightful theory to interpret the genomic consequences of
thermal adaptation to previous events of climate change beyond range shifts. However …

Genomic vulnerability to rapid climate warming in a tree species with a long generation time

B Dauphin, C Rellstab, M Schmid, S Zoller… - Global Change …, 2021 - Wiley Online Library
The ongoing increase in global temperature affects biodiversity, especially in mountain
regions where climate change is exacerbated. As sessile, long‐lived organisms, trees are …

Polygenic adaptation: integrating population genetics and gene regulatory networks

M Fagny, F Austerlitz - Trends in Genetics, 2021 - cell.com
The adaptation of populations to local environments often relies on the selection of optimal
values for polygenic traits. Here, we first summarize the results obtained from different …

How can genomics help or hinder wildlife conservation?

TL Schmidt, JA Thia, AA Hoffmann - Annual Review of Animal …, 2024 - annualreviews.org
Genomic data are becoming increasingly affordable and easy to collect, and new tools for
their analysis are appearing rapidly. Conservation biologists are interested in using this …

Connecting tree‐ring phenotypes, genetic associations and transcriptomics to decipher the genomic architecture of drought adaptation in a widespread conifer

C Depardieu, S Gérardi, S Nadeau… - Molecular …, 2021 - Wiley Online Library
As boreal forests face significant threats from climate change, understanding evolutionary
trajectories of coniferous species has become fundamental to adapting management and …