MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

Seizures result from hypersynchronous, abnormal firing of neuronal populations and are the
primary clinical symptom of the epilepsies. Brain tissue from animal models and patients …

Pericytes are positioned between brain capillary endothelial cells, astrocytes and neurons.
They degenerate in multiple neurological disorders. However, their role in the pathogenesis …

Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia.
These small noncoding RNAs bind to mRNAs containing complementary sequences and …

Brain plasticity refers to the ability of synaptic connections to adapt their function and
structure in response to experience, including environmental changes, sensory deprivation …

Growing evidence points to synaptic pathology as a core component of the pathophysiology
of schizophrenia (SZ). Significant reductions of dendritic spine density and altered …

Several experimental procedures are currently used to investigate the impact of the
environment on brain plasticity under physiological and pathological conditions. The …

Huntington's disease (HD) is an intractable neurodegenerative disorder caused by mutant
Huntingtin (HTT) proteins that adversely affect various biomolecules and genes. MicroRNAs …

In mice and other mammals, forebrain neurons integrate right and left eye information to
generate a three-dimensional representation of the visual environment. Neurons in the …

Stroke and subsequent cerebral ischemia/reperfusion (I/R) injury is a frequently occurring
disease that can have serious consequences in the absence of timely intervention. Circular …