The health effects of vitamin D supplementation: evidence from human studies
R Bouillon, D Manousaki, C Rosen… - Nature Reviews …, 2022 - nature.com
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children.
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …
Comparing the evidence from observational studies and randomized controlled trials for nonskeletal health effects of vitamin D
WB Grant, BJ Boucher, F Al Anouti, S Pilz - Nutrients, 2022 - mdpi.com
Although observational studies of health outcomes generally suggest beneficial effects with,
or following, higher serum 25-hydroxyvitamin D [25 (OH) D] concentrations, randomized …
or following, higher serum 25-hydroxyvitamin D [25 (OH) D] concentrations, randomized …
Non-linear Mendelian randomization analyses support a role for vitamin D deficiency in cardiovascular disease risk
A Zhou, JB Selvanayagam… - European Heart …, 2022 - academic.oup.com
Aims Low vitamin D status is associated with a higher risk for cardiovascular diseases
(CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null …
(CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null …
Vitamin D deficiency increases mortality risk in the UK biobank: a nonlinear mendelian randomization study
JP Sutherland, A Zhou, E Hyppönen - Annals of internal medicine, 2022 - acpjournals.org
Background: Low vitamin D status is associated with increased mortality, but randomized
trials on severely deficient participants are lacking. Objective: To assess genetic evidence …
trials on severely deficient participants are lacking. Objective: To assess genetic evidence …
Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update …
This assessment by the Environmental Effects Assessment Panel (EEAP) of the United
Nations Environment Programme (UNEP) provides the latest scientific update since our …
Nations Environment Programme (UNEP) provides the latest scientific update since our …
Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study
A Zhou, E Hyppönen - International Journal of Epidemiology, 2023 - academic.oup.com
Background Low vitamin D status is often associated with systemic low-grade inflammation
as reflected by elevated C-reactive protein (CRP) levels. We investigated the causality and …
as reflected by elevated C-reactive protein (CRP) levels. We investigated the causality and …
[HTML][HTML] Vitamin D and brain health: an observational and Mendelian randomization study
Background Higher vitamin D status has been suggested to have beneficial effects on the
brain. Objectives To investigate the association between 25-hydroxyvitamin D [25 (OH) D] …
brain. Objectives To investigate the association between 25-hydroxyvitamin D [25 (OH) D] …
Vitamin D and the central nervous system: Causative and preventative mechanisms in brain disorders
Twenty of the last one hundred years of vitamin D research have involved investigations of
the brain as a target organ for this hormone. Our group was one of the first to investigate …
the brain as a target organ for this hormone. Our group was one of the first to investigate …
Vitamin D in the Context of Evolution
C Carlberg - Nutrients, 2022 - mdpi.com
For at least 1.2 billion years, eukaryotes have been able to synthesize sterols and, therefore,
can produce vitamin D when exposed to UV-B. Vitamin D endocrinology was established …
can produce vitamin D when exposed to UV-B. Vitamin D endocrinology was established …
[HTML][HTML] Vitamin D and multiple health outcomes: an umbrella review of observational studies, randomized controlled trials, and Mendelian randomization studies
D Liu, X Meng, Q Tian, W Cao, X Fan, L Wu, M Song… - Advances in …, 2022 - Elsevier
Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …
(MR) studies have yielded inconsistent results on the associations of vitamin D …