Anemia in clinical practice—definition and classification: does hemoglobin change with aging?

MD Cappellini, I Motta - Seminars in hematology, 2015 - Elsevier
Anemia is a global public health problem affecting both developing and developed countries
at all ages. According to the World Health Organization (WHO), anemia is defined as …

[HTML][HTML] Sickle cell anaemia and malaria

L Luzzatto - Mediterranean journal of hematology and infectious …, 2012 - ncbi.nlm.nih.gov
Sickle cell anaemia is a major chapter within haemolytic anaemias; at the same time, its
epidemiology is a remarkable signature of the past and present world distribution of …

Antibody response after third BNT162b2 dose in recipients of allogeneic HSCT

R Redjoul, A Le Bouter, V Parinet, S Fourati… - The Lancet …, 2021 - thelancet.com
We previously reported a weak immune response after two doses of the vaccine against
SARS-CoV-2 in 36 (41%) of 88 recipients of allogeneic hematopoietic stem-cell …

Treating rare diseases in Africa: the drugs exist but the need is unmet

L Luzzatto, J Makani - Frontiers in Pharmacology, 2022 - frontiersin.org
Rare diseases (RD) pose serious challenges in terms of both diagnosis and treatment.
Legislation was passed in the US (1983) and in EU (2000) aimed to reverse the previous …

Hodgkin lymphoma at Groote Schuur Hospital, South Africa: the effect of HIV and bone marrow infiltration

L Swart, N Novitzky, Z Mohamed, J Opie - Annals of hematology, 2019 - Springer
Human immunodeficiency virus (HIV) is associated with an increased risk of developing
Hodgkin lymphoma (HL). South Africa (SA) has the highest HIV prevalence rate in the world …

Hydroxyurea—an essential medicine for sickle cell disease in Africa

L Luzzatto, J Makani - New England Journal of Medicine, 2019 - Mass Medical Soc
Higher levels of fetal hemoglobin (HbF) ameliorate the clinical course of sickle cell disease.
Hydroxyurea, an inhibitor of the enzyme ribonucleoside diphosphate reductase, increases …

A Journey from Blood Cells to Genes and Back

L Luzzatto - Annual Review of Genomics and Human Genetics, 2023 - annualreviews.org
I was attracted to hematology because by combining clinical findings with the use of a
microscope and simple laboratory tests, one could often make a diagnosis. I was attracted to …

Attitude, Perceived Barriers, and Challenges Toward Implementing Resource-Appropriate Guidelines for Hematologic Malignancies: Physicians' Survey in Ethiopia

OT Baissa, W Hailu, F Tadesse, A Abubeker… - JCO Global …, 2023 - ascopubs.org
PURPOSE Cancer care in low-income countries poses formidable challenges. Care may be
facilitated by resource-adapted guidelines, such as the National Comprehensive Cancer …

Haematology in sub-Saharan Africa: advances and opportunities in health care, education, and research

J Makani, G Moshi - The Lancet Haematology, 2021 - thelancet.com
Saying that blood is life is a bold and somewhat biased statement. Nevertheless, it sets the
tone for The Lancet Haematology Series on Haematological Care Priorities in Sub-Saharan …

Circulating Biomarkers for Alzheimer's Disease: Unlocking the diagnostic potential in Low-and Middle-Income Countries, focusing on Africa

L Nwamekang Belinga, J Espourteille… - 2024 - karger.com
Background: Alzheimer's disease (AD) is emerging as a significant public health challenge
in Africa, with predictions indicating a tripling in incidence by 2050. The diagnosis of AD on …