Astrogliosis and sexually dimorphic neurodegeneration and microgliosis in the olfactory bulb in Parkinson's disease
A Flores-Cuadrado, D Saiz-Sanchez… - npj Parkinson's …, 2021 - nature.com
Hyposmia is prodromal, and male sex is a risk marker for an enhanced likelihood ratio of
Parkinson's disease. The literature regarding olfactory bulb volume reduction is …
Parkinson's disease. The literature regarding olfactory bulb volume reduction is …
Proteoform Analysis of the Human Olfactory System: A Window into Neurodegenerative Diseases
E Rusi, F Pennacchia, WA Ruqa, G Talarico, G Bruno… - Proteomes, 2024 - mdpi.com
Background: Very little is known about the proteome of the human olfactory system and how
diseases associated with olfactory dysfunctions can affect it. With this review, we try to …
diseases associated with olfactory dysfunctions can affect it. With this review, we try to …
Transcriptomic insights into the response of the olfactory bulb to selenium treatment in a mouse model of Alzheimer's disease
R Zheng, ZH Zhang, YX Zhao, C Chen, SZ Jia… - International journal of …, 2019 - mdpi.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the
presence of extracellular senile plaques primarily composed of Aβ peptides and intracellular …
presence of extracellular senile plaques primarily composed of Aβ peptides and intracellular …
Proteomic Analysis of Human Breast Cancer MCF-7 Cells to Identify Cellular Targets of the Anticancer Pigment OR3 from Streptomyces coelicolor JUACT03
M Dammalli, VK Nadumane - Applied Biochemistry and Biotechnology, 2023 - Springer
Search for ideal compounds with known pathways of anticancer mechanism is still a priority
research focus for cancer, as it continues to be a major health challenge across the globe …
research focus for cancer, as it continues to be a major health challenge across the globe …
Proteomics of the human olfactory tract
Human olfactory tract plays a fundamental role in health and disease. Proteomic analysis of
the olfactory tract therefore bears fundamental importance for integrative biology and clinical …
the olfactory tract therefore bears fundamental importance for integrative biology and clinical …
Sensory modulation in mental health practice
Sensory modulation approaches have become increasingly prevalent in Australian mental
health practice over the past few years, but their use in UK mental health services remains in …
health practice over the past few years, but their use in UK mental health services remains in …
Smelling the dark proteome: functional characterization of PITH domain-containing protein 1 (C1orf128) in olfactory metabolism
M Lachén-Montes, N Mendizuri, K Ausín… - Journal of Proteome …, 2020 - ACS Publications
The Human Proteome Project (HPP) consortium aims to functionally characterize the dark
proteome. On the basis of the relevance of olfaction in early neurodegeneration, we have …
proteome. On the basis of the relevance of olfaction in early neurodegeneration, we have …
Neuronal and glial characterization in the rostrocaudal axis of the human anterior olfactory nucleus: Involvement in Parkinson's disease
S Villar-Conde, V Astillero-Lopez… - Frontiers in …, 2022 - frontiersin.org
Hyposmia is one of the prodromal symptoms of Parkinson's disease (PD) and a red flag in
clinical diagnosis. Neuropathologically, this sign correlates with α-synuclein involvement in …
clinical diagnosis. Neuropathologically, this sign correlates with α-synuclein involvement in …
Proteogenomics reveals orthologous alternatively spliced proteoforms in the same human and mouse brain regions with differential abundance in an Alzheimer's …
EMG da Silva, LGC Santos, FS de Oliveira, FCP Freitas… - Cells, 2021 - mdpi.com
Alternative splicing (AS) may increase the number of proteoforms produced by a gene.
Alzheimer's disease (AD) is a neurodegenerative disease with well-characterized AS …
Alzheimer's disease (AD) is a neurodegenerative disease with well-characterized AS …
SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology
SF Wade, AAM Diouara, B Ngom, F Thiam, N Dia - Microorganisms, 2024 - mdpi.com
Acute respiratory viruses (ARVs) are the leading cause of diseases in humans worldwide.
High-risk individuals, including children and the elderly, could potentially develop severe …
High-risk individuals, including children and the elderly, could potentially develop severe …