The role of ROS in tumour development and progression
EC Cheung, KH Vousden - Nature Reviews Cancer, 2022 - nature.com
Eukaryotic cells have developed complex systems to regulate the production and response
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …
Inflammation-induced DNA damage, mutations and cancer
The relationships between inflammation and cancer are varied and complex. An important
connection linking inflammation to cancer development is DNA damage. During …
connection linking inflammation to cancer development is DNA damage. During …
Cellular mechanisms and physiological consequences of redox-dependent signalling
KM Holmström, T Finkel - Nature reviews Molecular cell biology, 2014 - nature.com
Reactive oxygen species (ROS), which were originally characterized in terms of their
harmful effects on cells and invading microorganisms, are increasingly implicated in various …
harmful effects on cells and invading microorganisms, are increasingly implicated in various …
[HTML][HTML] Reactive oxygen species in inflammation and tissue injury
SM Rizwan, P ReddySekhar… - Antioxidants & redox …, 2014 - liebertpub.com
Reactive oxygen species (ROS) are key signaling molecules that play an important role in
the progression of inflammatory disorders. An enhanced ROS generation by …
the progression of inflammatory disorders. An enhanced ROS generation by …
[HTML][HTML] Oxidative stress and antioxidant defense
Reactive oxygen species (ROS) are produced by living organisms as a result of normal
cellular metabolism and environmental factors, such as air pollutants or cigarette smoke …
cellular metabolism and environmental factors, such as air pollutants or cigarette smoke …
Reactive oxygen species in cancer
GY Liou, P Storz - Free radical research, 2010 - Taylor & Francis
Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …
where they promote many aspects of tumour development and progression. However …
Reactive oxygen species regulate T cell immune response in the tumor microenvironment
X Chen, M Song, B Zhang… - Oxidative Medicine and …, 2016 - Wiley Online Library
Reactive oxygen species (ROS) produced by cellular metabolism play an important role as
signaling messengers in immune system. ROS elevated in the tumor microenvironment are …
signaling messengers in immune system. ROS elevated in the tumor microenvironment are …
Free radicals and antioxidants in normal physiological functions and human disease
M Valko, D Leibfritz, J Moncol, MTD Cronin… - The international journal …, 2007 - Elsevier
Reactive oxygen species (ROS) and reactive nitrogen species (RNS, eg nitric oxide, NO) are
well recognised for playing a dual role as both deleterious and beneficial species. ROS and …
well recognised for playing a dual role as both deleterious and beneficial species. ROS and …
Free radicals, metals and antioxidants in oxidative stress-induced cancer
M Valko, CJB Rhodes, J Moncol, MM Izakovic… - Chemico-biological …, 2006 - Elsevier
Oxygen-free radicals, more generally known as reactive oxygen species (ROS) along with
reactive nitrogen species (RNS) are well recognised for playing a dual role as both …
reactive nitrogen species (RNS) are well recognised for playing a dual role as both …
The Mesangial cell—the glomerular stromal cell
Mesangial cells are stromal cells that are important for kidney glomerular homeostasis and
the glomerular response to injury. A growing body of evidence demonstrates that …
the glomerular response to injury. A growing body of evidence demonstrates that …