Poly (lactic-co-glycolic acid) microsphere production based on quality by design: a review

Y Hua, Y Su, H Zhang, N Liu, Z Wang, X Gao, J Gao… - Drug Delivery, 2021 - Taylor & Francis
Poly (lactic-co-glycolic acid)(PLGA) has garnered increasing attention as a candidate drug
delivery polymer owing to its favorable properties, including its excellent biocompatibility …

Microfluidic assisted synthesis of PLGA drug delivery systems

S Rezvantalab, MK Moraveji - RSC advances, 2019 - pubs.rsc.org
Poly (lactic-co-glycolic acid)(PLGA) is a biocompatible and biodegradable polymer that
recently attracted attention for use as part of drug delivery systems (DDS). In this context …

Particle engineering principles and technologies for pharmaceutical biologics

D Cun, C Zhang, H Bera, M Yang - Advanced Drug Delivery Reviews, 2021 - Elsevier
The global market of pharmaceutical biologics has expanded significantly during the last few
decades. Currently, pharmaceutical biologic products constitute an indispensable part of the …

Microfluidic synthesis of nanomaterials for biomedical applications

Y Huang, C Liu, Q Feng, J Sun - Nanoscale Horizons, 2023 - pubs.rsc.org
The field of nanomaterials has progressed dramatically over the past decades with important
contributions to the biomedical area. The physicochemical properties of nanomaterials, such …

Quality by design thinking in the development of long-acting injectable PLGA/PLA-based microspheres for peptide and protein drug delivery

C Zhang, L Yang, F Wan, H Bera, D Cun… - International journal of …, 2020 - Elsevier
Abstract Adopting the Quality by Design (QbD) approach in the drug development process
has transformed from “nice-to-do” into a crucial and required part of the development …

Recent advances in the design of microfluidic technologies for the manufacture of drug releasing particles

A Forigua, RL Kirsch, SM Willerth, KS Elvira - Journal of Controlled Release, 2021 - Elsevier
Drug releasing particles are valued for their ability to deliver therapeutics to targeted
locations and for their controllable release patterns. The development of microfluidic …

Multipolymer microsphere delivery of SARS-CoV-2 antigens

F Shahjin, M Patel, J Machhi, JD Cohen, MU Nayan… - Acta Biomaterialia, 2023 - Elsevier
Effective antigen delivery facilitates antiviral vaccine success defined by effective immune
protective responses against viral exposures. To improve severe acute respiratory syndrome …

Formulation of tunable size PLGA-PEG nanoparticles for drug delivery using microfluidic technology

AG Mares, G Pacassoni, JS Marti, S Pujals… - PLoS …, 2021 - journals.plos.org
Amphiphilic block co-polymer nanoparticles are interesting candidates for drug delivery as a
result of their unique properties such as the size, modularity, biocompatibility and drug …

Recent fabrication methods to produce polymer-based drug delivery matrices (Experimental and In Silico Approaches)

A Procopio, E Lagreca, R Jamaledin, S La Manna… - Pharmaceutics, 2022 - mdpi.com
The study of novel drug delivery systems represents one of the frontiers of the biomedical
research area. Multi-disciplinary scientific approaches combining traditional or engineered …

On the inherent properties of Soluplus and its application in ibuprofen solid dispersions generated by microwave-quench cooling technology

NQ Shi, HW Lai, Y Zhang, B Feng, X Xiao… - Pharmaceutical …, 2018 - Taylor & Francis
Polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer, or Soluplus®,
is a relatively new copolymer and a promising carrier of amorphous solid dispersions …