[HTML][HTML] The role of the PI3K/AKT signalling pathway in the corneal epithelium: recent updates
K Chen, Y Li, X Zhang, R Ullah, J Tong, Y Shen - Cell death & disease, 2022 - nature.com
Abstract Phosphatidylinositol 3 kinase (PI3K)/AKT (also called protein kinase B, PKB)
signalling regulates various cellular processes, such as apoptosis, cell proliferation, the cell …
signalling regulates various cellular processes, such as apoptosis, cell proliferation, the cell …
[HTML][HTML] Niosomal drug delivery systems for ocular disease—Recent advances and future prospects
S Durak, M Esmaeili Rad, A Alp Yetisgin, H Eda Sutova… - Nanomaterials, 2020 - mdpi.com
The eye is a complex organ consisting of several protective barriers and particular defense
mechanisms. Since this organ is exposed to various infections, genetic disorders, and visual …
mechanisms. Since this organ is exposed to various infections, genetic disorders, and visual …
Super-cationic carbon quantum dots synthesized from spermidine as an eye drop formulation for topical treatment of bacterial keratitis
HJ Jian, RS Wu, TY Lin, YJ Li, HJ Lin, SG Harroun… - ACS …, 2017 - ACS Publications
We have developed a one-step method to synthesize carbon quantum dots (CQDPAs) from
biogenic polyamines (PAs) as an antibacterial agent for topical treatment of bacterial …
biogenic polyamines (PAs) as an antibacterial agent for topical treatment of bacterial …
[PDF][PDF] An ocular commensal protects against corneal infection by driving an interleukin-17 response from mucosal γδ T cells
Mucosal sites such as the intestine, oral cavity, nasopharynx, and vagina all have
associated commensal flora. The surface of the eye is also a mucosal site, but proof of a …
associated commensal flora. The surface of the eye is also a mucosal site, but proof of a …
Functional carbon quantum dots for ocular imaging and therapeutic applications
VB Kumar, I Sher, S Rencus‐Lazar, Y Rotenstreich… - Small, 2023 - Wiley Online Library
Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have
received considerable attention due to their excellent fluorescent properties, extremely small …
received considerable attention due to their excellent fluorescent properties, extremely small …
Carbonized nanogels for simultaneous antibacterial and antioxidant treatment of bacterial keratitis
To prevent visual loss, clinical therapy of severe bacterial keratitis (BK) demands
simultaneous remedying of the damage caused by bacterial infection and its induced …
simultaneous remedying of the damage caused by bacterial infection and its induced …
BCLA CLEAR-Contact lens wettability, cleaning, disinfection and interactions with tears
Contact lens materials have undergone significant changes over the past 20 years,
particularly with respect to the introduction of silicone hydrogel materials. Whilst this …
particularly with respect to the introduction of silicone hydrogel materials. Whilst this …
[HTML][HTML] Innate immune system activation, inflammation and corneal wound healing
N Fortingo, S Melnyk, SH Sutton, MA Watsky… - International journal of …, 2022 - mdpi.com
Corneal wounds resulting from injury, surgeries, or other intrusions not only cause pain, but
also can predispose an individual to infection. While some inflammation may be beneficial to …
also can predispose an individual to infection. While some inflammation may be beneficial to …
[HTML][HTML] Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy
J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …
related conditions, pose considerable challenges to effective management and treatment …
Ferrous sulfate-loaded hydrogel cures Staphylococcus aureus infection via facilitating a ferroptosis-like bacterial cell death in a mouse keratitis model
Hydrogels loaded with ampicillin, vancomycin or other antibiotics are one of the most widely
used therapeutic agents for keratitis caused by Staphylococcus aureus. However …
used therapeutic agents for keratitis caused by Staphylococcus aureus. However …