A Decade's Progress in the Development of Molecular Imaging Agents Targeting the Growth Hormone Secretagogue Receptor

MD Childs, LG Luyt - Molecular Imaging, 2020 - journals.sagepub.com
The growth hormone secretagogue receptor 1a (GHSR), also called the ghrelin receptor, is
a G protein-coupled receptor known to play an important metabolic role in the regulation of …

Design, Synthesis, and Preclinical Evaluation of a High-Affinity 18F-Labeled Radioligand for Myocardial Growth Hormone Secretagogue Receptor Before and After …

R Sullivan, J Hou, L Yu, B Wilk, J Sykes… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
The peptide hormone ghrelin is produced in cardiomyocytes and acts through the
myocardial growth hormone secretagogue receptor (GHSR) to promote cardiomyocyte …

[HTML][HTML] Shielding the Gut: Ghrelin and Ferrostatin-1's Protective Role Against Sepsis-Induced Intestinal Ferroptosis

Q Hou, Z Dou, L Zhu, B Li - Biomedicines, 2024 - mdpi.com
Objective: This study investigates the therapeutic efficacy of ghrelin in alleviating sepsis-
induced intestinal damage, focusing on its potential to inhibit ferroptosis and protect …

Traceable peptidic ligands that target ghrelin receptors

M Liu, J Wade, MA Hossain - Current Protein and Peptide …, 2020 - ingentaconnect.com
Ghrelin is a 28-amino acid octanoylated peptide hormone that is implicated in many
physiological and pathophysiological processes. Specific visualization of ghrelin and its …

Molecular Mechanisms Regulating the Platelet Thrombin Receptor PAR4

PE Thibeault - 2020 - search.proquest.com
Abstract Proteinase activated receptor 4 (PAR4) is a G-protein-coupled receptor with an
important role in the platelet response to vascular injury. In platelets, PAR4 activation, by …