Amino acids form peptides and proteins and are therefore considered the main building
blocks of life. The kidney has an important but under-appreciated role in the synthesis …

Chronic kidney disease (CKD), defined as persistent (> 3 months) kidney functional loss,
has a growing prevalence (> 10% worldwide population) and limited treatment options …

Ketogenic dietary interventions (KDIs) are beneficial in animal models of autosomal-
dominant polycystic kidney disease (ADPKD). KETO-ADPKD, an exploratory, randomized …

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of
numerous kidney cysts which leads to kidney failure. ADPKD is responsible for …

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized
by kidney cyst formation and progressive kidney function loss. Dietary interventions such as …

Autosomal Dominant Polycystic Kidney Disease (ADPKD) leads to end stage kidney
disease (ESKD) through the development and expansion of multiple cysts throughout the …

Autosomal polycystic kidney disease is the most common inherited kidney disease
determining 5% of all end-stage kidney disease. The only therapy approved for this …

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Background Dysregulated energy metabolism is a recently discovered key feature of
autosomal dominant polycystic kidney disease (ADPKD). Cystic cells depend on glucose …

Background: Recent findings have highlighted that abnormal energy metabolism is a key
feature of autosomal-dominant polycystic kidney disease (ADPKD). Emerging evidence …