Immune-mediated cytokine storm and its role in severe dengue

A Srikiatkhachorn, A Mathew, AL Rothman - Seminars in …, 2017 - Springer
Dengue remains one of the most important mosquito-borne diseases worldwide. Infection
with one of the serologically related dengue viruses (DENVs) can lead to a wide range of …

Pathogenesis of Crimean-Congo hemorrhagic fever

E Akıncı, H Bodur, H Leblebicioglu - Vector-Borne and Zoonotic …, 2013 - liebertpub.com
Abstract Although Crimean-Congo hemorrhagic fever (CCHF) is a widespread tick-borne
disease, little is known about its pathogenesis. The interaction of the virus with host cells is …

[HTML][HTML] The pathology of severe dengue in multiple organs of human fatal cases: histopathology, ultrastructure and virus replication

TF Póvoa, AMB Alves, CAB Oliveira, GJ Nuovo… - PloS one, 2014 - journals.plos.org
Dengue is a public health problem, with several gaps in understanding its pathogenesis.
Studies based on human fatal cases are extremely important and may clarify some of these …

[HTML][HTML] Infections at the nexus of metabolic-associated fatty liver disease

J Boeckmans, M Rombaut, T Demuyser… - Archives of …, 2021 - Springer
Metabolic-associated fatty liver disease (MAFLD) is a chronic liver disease that affects about
a quarter of the world population. MAFLD encompasses different disease stadia ranging …

Dengue virus infection: current concepts in immune mechanisms and lessons from murine models

R Guabiraba, B Ryffel - Immunology, 2014 - Wiley Online Library
Dengue viruses (DENV), a group of four serologically distinct but related flaviviruses, are
responsible for one of the most important emerging viral diseases. This mosquito‐borne …

[HTML][HTML] Autoimmunity in dengue pathogenesis

SW Wan, CF Lin, TM Yeh, CC Liu, HS Liu… - Journal of the Formosan …, 2013 - Elsevier
Dengue is one of the most important vector-borne viral diseases. With climate change and
the convenience of travel, dengue is spreading beyond its usual tropical and subtropical …

[HTML][HTML] SB203580 modulates p38 MAPK signaling and dengue virus-induced liver injury by reducing MAPKAPK2, HSP27, and ATF2 phosphorylation

GP Sreekanth, A Chuncharunee, A Sirimontaporn… - PloS one, 2016 - journals.plos.org
Dengue virus (DENV) infection causes organ injuries, and the liver is one of the most
important sites of DENV infection, where viral replication generates a high viral load. The …

Liver involvement in dengue viral infections

HA Dissanayake, SL Seneviratne - Reviews in medical virology, 2018 - Wiley Online Library
Dengue fever is the commonest viral haemorrhagic fever worldwide and is a leading cause
of morbidity and mortality in the tropics. Dengue viral infections are frequently associated …

[HTML][HTML] Inhibitory effect of glutathione on oxidative liver injury induced by dengue virus serotype 2 infections in mice

J Wang, Y Chen, N Gao, Y Wang, Y Tian, J Wu… - PloS one, 2013 - journals.plos.org
The pathogenesis of dengue virus (DV) infection has not been completely defined and
change of redox status mediated by depletion of glutathione (GSH) in host cell is a common …

Identification and molecular characterization of a novel duck Tembusu virus isolate from Southwest China

K Zhu, J Huang, R Jia, B Zhang, M Wang, D Zhu… - Archives of …, 2015 - Springer
Tembusu virus (TMUV) has caused significant economic losses in the Chinese duck industry
and may have been overlooked regarding its zoonotic transmission potential. A novel TMUV …