CGRP sensory neurons promote tissue healing via neutrophils and macrophages

YZ Lu, B Nayer, SK Singh, YK Alshoubaki, E Yuan… - Nature, 2024 - nature.com
The immune system has a critical role in orchestrating tissue healing. As a result,
regenerative strategies that control immune components have proved effective,. This is …

Cell therapy in the cornea: the emerging role of microenvironment

G Suanno, VG Genna, E Maurizi, AA Dieh… - Progress in Retinal and …, 2024 - Elsevier
The cornea is an ideal testing field for cell therapies. Its highly ordered structure, where
specific cell populations are sequestered in different layers, together with its accessibility …

Chronobiological and neuroendocrine insights into dry eye

L Li, H Li, B Chen - Trends in Molecular Medicine, 2024 - cell.com
Dry eye, a prevalent ocular surface disease, is significantly influenced by modern lifestyle
factors such as night-shift work and extended screen time. Emerging evidence suggests a …

Impaired Tertiary Dentin Secretion After Shallow Injury in Tgfbr2-Deficient Dental Pulp Cells Is Rescued by Extended CGRP Signaling

M Stanwick, F Fenesha, A Hamid, K Kang… - International Journal of …, 2024 - mdpi.com
The transforming growth factor β (TGFβ) superfamily is a master regulator of development,
adult homeostasis, and wound repair. Dysregulated TGFβ signaling can lead to cancer …

[HTML][HTML] CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

L Ma, L Yang, X Wang, L Zhao, X Bai… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: This study aims to elucidate the calcitonin gene-related peptide (CGRP) mediation
and primary mechanism of corneal sensory nerves on tear production of the lacrimal gland …

Overexpression of CGRP receptor attenuates tendon graft degeneration in anterior cruciate ligament reconstruction

X Zhao, Z Cai, Y Luo, Z Lin… - Journal of Orthopaedic …, 2025 - Wiley Online Library
Cell apoptosis or necrosis, extracellular matrix loss, and excessive inflammation may induce
tendon graft degeneration. The impairment in the regeneration capability of nerve fibers and …

Multidimensional immunotherapy for dry eye disease: current status and future directions

D Huang, Z Li - Frontiers in Ophthalmology, 2024 - frontiersin.org
Dry Eye Disease (DED) is a multifactorial condition driven by tear film hyperosmolarity,
immune dysregulation, and neuro-immune interactions. The immune system plays a central …

[HTML][HTML] The healing power of sensory neurons: New horizons for diabetic and neuropathic tissue repair

YZ Lu, S Ramakrishnan… - Clinical and Translational …, 2024 - pmc.ncbi.nlm.nih.gov
The healing power of sensory neurons: New horizons for diabetic and neuropathic tissue repair
- PMC Skip to main content Here's how you know Official websites use .gov A .gov website …

Morphological aberration of corneal nerves in hyposecretory dry eye guinea pigs

T Kiyoi, Q He, L Liu, S Zheng, H Nakazawa… - Medical Molecular …, 2024 - Springer
Dry eye, a common ocular surface disease associated with tear film instability and corneal
impairment, is frequently accompanied by ocular discomfort and pain. Recent research has …

The Relationship between Smoking and Obstructive Sleep Apnea (OSA) in Students at the Faculty of Law, Indonesian Christian University Class (2018-2021)

L Marlina, FH Poluan - Journal of Complementary and …, 2024 - research.manuscritpub.com
Obstructive Sleep Apnea (OSA) is a condition of obstruction/narrowing of the upper airway
during sleep, which results in cessation of breathing for some time. OSA can be experienced …