Challenges and guidelines for clinical trial of herbal drugs

A Parveen, B Parveen, R Parveen… - Journal of Pharmacy …, 2015 - journals.lww.com
Abstract World Health Organization (WHO) has defined herbal medicines as finished
labeled medicinal product that contain an active ingredient, aerial, or underground parts of …

Clinical progress on management of pneumonia due to COVID-19 with Chinese traditional patent medicines

Y Wu, P Zhong - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: The outbreak of new coronavirus has tremendously threatened the public
health system worldwide, including China. Chinese patent medicines (CPMs) have greatly …

[HTML][HTML] Efficacy and safety of Reduning injection in the treatment of COVID-19: a randomized, multicenter clinical study

X Xu, J Zhang, W Zheng, Z Yang, X Zhao… - Annals of palliative …, 2021 - apm.amegroups.org
Background: Reduning injection is a traditional Chinese medicine (TCM) with known
efficacy against a variety of viral infections, but there is no data about its efficacy against …

Efficacy and safety of ReDuNing injection as a treatment for COVID-19 and its inhibitory effect against SARS-CoV-2

Q Ma, Y Xie, Z Wang, B Lei, R Chen, B Liu… - Journal of …, 2021 - Elsevier
Background Although the rapid emergence of coronavirus disease 2019 (COVID-19) poses
a considerable threat to global public health, no specific treatment is available for COVID-19 …

Epidemiological and etiological characteristics of hand, foot and mouth disease in Henan, China, 2008–2013

X Huang, H Wei, S Wu, Y Du, L Liu, J Su, Y Xu… - Scientific reports, 2015 - nature.com
Hand, foot and mouth disease (HFMD) is a common childhood illness caused by
enteroviruses. HFMD outbreaks and reported cases have sharply increased in China since …

Fever and antipyretic supported by traditional Chinese medicine: a multi-pathway regulation

LL Ma, HM Liu, CH Luo, YN He, F Wang… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease, 2019 (COVID-19), has spread rapidly around the world and
become a major public health problem facing the world. Traditional Chinese medicine …

Insight into the molecular mechanism of a herbal injection by integrating network pharmacology and in vitro

Y Ma, X Zhang, Z Su, N Li, L Cao, G Ding… - Journal of …, 2015 - Elsevier
Chinese medical herbs could treat complex diseases through the synergistic effect of multi-
components, multi-targets and multi-channels. However, it was difficult to systematically …

Active ingredients of reduning injection maintain high potency against SARS-CoV-2 variants

Z Xiao, H Xu, Z Qu, X Ma, B Huang, M Sun… - Chinese journal of …, 2023 - Springer
Objective To investigate the anti-coronavirus potential and the corresponding mechanisms
of the two ingredients of Reduning Injection: quercetin and luteolin. Methods A pseudovirus …

Serum and urine metabolomics based on UPLC-Q-TOF/MS reveals the antipyretic mechanism of Reduning injection in a rat model

X Gao, C Huang, T Geng, X Chen, J Wang, J Liu… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Reduning injection (RDN), a patented traditional Chinese
medicine, has the obvious antipyretic effect and has been widely used in China. Although …

[HTML][HTML] Comparative study of the efficacy and pharmacokinetics of reduning injection and atomization inhalation

G Zhang, Y Li, T Chen, Y Gao, J Sun, W Yang… - Biomedicine & …, 2019 - Elsevier
The effects of Reduning injection and nebulized inhalation for treating upper respiratory tract
infections were compared, including anti-bacterial, anti-viral, anti-inflammatory, anti-pyretic …