Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Long-read sequencing technologies have substantially improved the assemblies of many
isolate bacterial genomes as compared to fragmented short-read assemblies. However …

Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Large-scale bacterial population genetics studies are now routine due to cost-effective
Illumina short-read sequencing. However, analysing plasmid content remains difficult due to …

Illumina sequencing platforms have enabled widespread bacterial whole genome
sequencing. While Illumina data is appropriate for many analyses, its short read length limits …

Plasmids are mobile genetics elements that play an important role in the environmental
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …

Antimicrobial resistance (AMR) is a global health crisis that poses a great threat to modern
medicine. Effective prevention strategies are urgently required to slow the emergence and …

Klebsiella pneumoniae has emerged as an important cause of two distinct public health
threats: multi-drug resistant (MDR) healthcare-associated infections and drug susceptible …