[HTML][HTML] Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Therapeutic interventions in patients with prolonged disorders of consciousness

A Thibaut, N Schiff, J Giacino, S Laureys… - The Lancet …, 2019 - thelancet.com
The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

[HTML][HTML] Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions

BL Edlow, LRD Sanz, L Polizzotto, N Pouratian… - Neurocritical care, 2021 - Springer
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

[HTML][HTML] Mapping the subcortical connectivity of the human default mode network

J Li, WH Curley, B Guerin, DD Dougherty, AV Dalca… - Neuroimage, 2021 - Elsevier
The default mode network (DMN) mediates self-awareness and introspection, core
components of human consciousness. Therapies to restore consciousness in patients with …

[HTML][HTML] Proceedings of the first curing coma campaign NIH symposium: challenging the future of research for coma and disorders of consciousness

J Claassen, Y Akbari, S Alexander, MK Bader, K Bell… - Neurocritical care, 2021 - Springer
Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden
for patients, families, and society worldwide. As part of the Curing Coma Campaign, the …

Measuring consciousness in severely damaged brains

O Gosseries, H Di, S Laureys… - Annual Review of …, 2014 - annualreviews.org
Significant advances have been made in the behavioral assessment and clinical
management of disorders of consciousness (DOC). In addition, functional neuroimaging …

Minimum competency recommendations for programs that provide rehabilitation services for persons with disorders of consciousness: a position statement of the …

JT Giacino, J Whyte, R Nakase-Richardson… - Archives of physical …, 2020 - Elsevier
Persons who have disorders of consciousness (DoC) require care from multidisciplinary
teams with specialized training and expertise in management of the complex needs of this …

Sham‐controlled randomized multicentre trial of transcranial direct current stimulation for prolonged disorders of consciousness

A Thibaut, F Fregni, A Estraneo… - European Journal of …, 2023 - Wiley Online Library
Background and purpose Transcranial direct current stimulation (tDCS) has been shown to
improve signs of consciousness in a subset of patients with disorders of consciousness …

[HTML][HTML] Current and potential pharmacologic therapies for traumatic brain injury

J Tani, YT Wen, CJ Hu, JY Sung - Pharmaceuticals, 2022 - mdpi.com
The present article reviewed the pharmacologic therapies of traumatic brain injury (TBI),
including current and potential treatments. Pharmacologic therapies are an essential part of …

Disorders of consciousness

BC Eapen, J Georgekutty, B Subbarao… - Physical Medicine …, 2017 - pmr.theclinics.com
Annually, approximately 2.5 million people sustain a traumatic brain injury (TBI) in the
United States, and more than 5.3 million people live with a TBI-related disability. TBI not only …