Intercalated cells (ICs) are found in the connecting tubule and the collecting duct. Of the
three IC subtypes identified, type B intercalated cells are one of the best characterized and …

Pendrin is a Na+-independent Cl−/HCO3− exchanger that localizes to type B and non-A,
non-B intercalated cells, which are expressed within the aldosterone-sensitive region of the …

We characterized mouse blood pressure and ion transport in the setting of commonly used
rodent diets that drive K+ intake to the extremes of deficiency and excess. Male 129S2/Sv …

Pendrin is an intercalated cell Cl−/HCO 3− exchanger thought to participate in K+-sparing
NaCl absorption. However, its role in K+ homeostasis has not been clearly defined. We …

Both KCC3b and KCC3a seem to be needed for maintaining cell volume during enhanced
inward cotransport of Na-glucose in proximal tubule and Na-HCO 3 in intercalated cells. In …

Within the CCD of the distal nephron of the rabbit, the BK (maxi K) channel mediates Ca2+-
and/or stretch-dependent flow-induced K+ secretion (FIKS) and contributes to K+ adaptation …

The prevalence and spectrum of sequence alterations in the SLC26A4 gene, which codes
for the anion exchanger pendrin, are population-specific and account for at least 50% of …

Type B and non-A, non-B intercalated cells are found within the connecting tubule and the
cortical collecting duct. Of these cell types, type B intercalated cells are known to mediate …

Abstract Background/Aims: Pendrin is a Cl-/I-/HCO3-exchanger playing a fundamental role
in controlling blood pressure and airway function, therefore representing an attractive target …

Sequence alterations in the pendrin gene (SLC26A4) leading to functionally affected protein
variants are frequently involved in the pathogenesis of syndromic and nonsyndromic …