Background Cancer is one of the greatest public health challenges worldwide, and we still
lack complementary approaches to significantly enhance the efficacy of standard anticancer …

Glioblastoma (GBM) is a devastating type of brain tumor, and current therapeutic treatments,
including surgery, chemotherapy, and radiation, are palliative at best. The design of effective …

The vulnerability of cancer cells to nutrient deprivation and their dependency on specific
metabolites are emerging hallmarks of cancer. Fasting or fasting-mimicking diets (FMDs) …

Over the past decade, the search for dietary factors on which to base cancer prevention
guidelines has led to the rapid expansion of the field of dietary patterns and cancer. Multiple …

Many cancers have long been thought to primarily metabolize glucose for energy production—
a phenomenon known as the Warburg Effect, after the classic studies of Otto Warburg in the …

The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative
energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic …

Although cancer is still one of the most significant global challenges facing public health, the
world still lacks complementary approaches that would significantly enhance the efficacy of …

Glioblastoma is one of the most lethal human cancers, with poor survival despite surgery,
radiation treatment, and chemotherapy. Advances in the treatment of this type of brain tumor …

Background Ketogenic metabolic therapy (KMT) using ketogenic diets (KD) is emerging as
viable alternative or complementary strategy for managing cancer; however, few clinical …

In recent years dietary interventions have become a promising tool in cancer treatment and
have demonstrated a powerful ability to alter metabolism and tumor growth, development …