Mitogen-activated protein kinase (MAPK)-activated protein kinases (MAPKAPKs) are
defined by their exclusive activation by MAPKs. They can be activated by classical and …

Abstract Protein phosphatase 2A (PP2A) is a highly complex heterotrimeric enzyme that
catalyzes the selective removal of phosphate groups from protein serine and threonine …

In this study, we detail a novel approach that combines bacterial fitness fluorescent reporter
strains with scRNA-seq to simultaneously acquire the host transcriptome, surface marker …

Tristetraprolin (TTP) is an RNA-destabilizing protein that exerts profound anti-inflammatory
effects by inhibiting the expression of tumour necrosis factor and many other inflammatory …

RNA-binding protein tristetraprolin (TTP) plays a fundamental role in various physiological
and pathological processes including differentiation, reprogramming, metabolism …

Simple Summary Chronic inflammatory diseases account for up to 60% of deaths worldwide
and, thus, are considered a great threat for human health by the World Health Organization …

ZC3H11A is a cellular protein associated with the transcription export (TREX) complex that
is induced during heat-shock. Several nuclear-replicating viruses exploit the mRNA export …

The chemokine CXCL4 has been implicated in several immune diseases. Exposure of
monocyte-derived dendritic cells (moDCs) to CXCL4 potentiates the production of …

Abstract AU-rich element (ARE)-mediated mRNA decay represents a key mechanism to
avoid excessive production of inflammatory cytokines. Tristetraprolin (TTP, encoded by …

Inflammation is a crucial part of immune responses towards invading pathogens or tissue
damage. While inflammatory reactions are aimed at removing the triggering stimulus, it is …