The total and regional peripheral resistance and capacitance of the vascular system is
regulated by the sympathetic nervous system, which influences the vasculature mainly …

Ringer bicarbonate solution containing isolated precontracted strips of bovine coronary
artery caused a rapid and pronounced, but transient, relaxant response that was …

Nitric oxide (NO) synthesized from L-arginine is a ubiquitous intracellular chemical
messenger and is involved in signal transduction in diverse mammalian cells, including …

trans-Resveratrol (t-RESV; 1–10 μM), a phenolic component of wines, had no effect on
phenylephrine-(PE; 1 μM) and high KCl-(60 mM) induced contractions in endothelium …

We studied the effects of hypercholesterolemia on vascular responsiveness in different
arteries isolated from rabbits: control groups of rabbits and groups receiving the atherogenic …

Materials and Methods Preparation of rat and rabbit aortic rings and tension re cording. The
preparation of rat and rabbit aortic rings was similar to that described previously (Furchgott …

In the last few years, experimental evidence has accumulated which suggests a substantial
role for the endothelium in the control of vascular tone. Endothelium-dependent dilatations …

Abstract α-Adrenoceptors may be subdivided based on their anatomical distribution within
the synapse. Presynaptic α-adrenoceptors are generally of the α 2-subtype and modulate …

Major advances have been made in our understanding of the molecular structure and
function of the α-adrenoceptors. Many new subtypes of the α-adrenoceptor have been …

The selective cyclic GMP phosphodiesterase inhibitor M&B 22948 and the less selective
phosphodiesterase inhibitors papavenne and isobutylmethyixanthine(IBMX) eath indUced a …