Background In the last decades, studies have estimated the upper gastrointestinal tract
bleeding/perforation (UGIB) risk associated with individual nonsteroidal anti-inflammatory …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are probably the most common cause of
gastroduodenal injury in the United States today. Approximately half of patients who …

Background The relation between H pylori infection and use of non-steroidal anti-
inflammatory drugs (NSAIDs) in the pathogenesis of peptic-ulcer disease is controversial …

Background Misoprostol is effective for ulcers associated with the use of nonsteroidal
antiinflammatory drugs (NSAIDs) but is often poorly tolerated because of diarrhea and …

Background Suppressing acid secretion is thought to reduce the risk of ulcers associated
with regular use of nonsteroidal antiinflammatory drugs (NSAIDs), but the best means of …

Background Many patients who have had upper gastrointestinal bleeding continue to take
low-dose aspirin for cardiovascular prophylaxis or other nonsteroidal antiinflammatory drugs …

By inhibiting prostaglandin synthesis, nonsteroidal anti-inflammatory drugs (NSAIDs)
compromise gastroduodenal defense mechanism including blood flow and …

Guidelines are developed under the auspices of the American College of Gastroenterology
and its Practice Parameters Committee and approved by the Board of Trustees. Each has …

Aims Because of the widespread use of aspirin for prevention of cardiovascular diseases,
side‐effects associated with thromboprophylactic doses are of interest. This study …

Summary Background The effect of Helicobacter pylori in patients receiving non-steroidal
anti-inflammatory drugs (NSAIDs) is unclear. We investigated the effects of H pylori …