Sperm plasma membrane lipids are essential for the function and integrity of mammalian
spermatozoa. Various lipid types are involved in each key step within the fertilization …

Genetically modified pigs have become valuable tools for generating advances in animal
agriculture and human medicine. Importantly, in vitro production and manipulation of …

Zinc (Zn) is a critical microelement for physiological process, but excess exposure can cause
testicular dysfunction. However, the underlying mechanism of Zn-induced ferroptosis via …

Alkalinization of sperm cytosol is essential for plasma membrane hyperpolarization,
hyperactivation of motility, and acrosomal exocytosis during sperm capacitation in mammals …

Sperm-zona pellucida (ZP) interaction, involving the binding of sperm surface ligands to
complementary carbohydrates of ZP, is the first direct gamete contact event crucial for …

Sperm capacitation is a post-testicular maturation step endowing spermatozoa with
fertilizing capacity within the female reproductive tract, significant for fertility, reproductive …

Background The assessment of sperm DNA integrity has been proposed as a
complementary test to conventional mammalian semen analysis. In this sense, single-strand …

tRNA-derived small RNAs (tsRNAs) from spermatozoa could act as acquired epigenetic
factors and contribute to offspring phenotypes. However, the roles of specific tsRNAs in early …

Background Porcine seminal plasma (SP) is endowed with a heterogeneous population of
extracellular vesicles (sEVs). This study evaluated the immunophenotypic profile by high …

Whether basal metabolic activity in sperm has any influence on their fertilising capacity has
not been explored. Using the pig as a model, the present study investigated the relationship …