Microglia were first recognized as a distinct cell population in the CNS one century ago. For
a long time, they were primarily considered to be phagocytes responsible for removing …

Alzheimer's disease is a devastating neurodegenerative disorder with no cure. Countless
promising therapeutics have shown efficacy in rodent Alzheimer's disease models yet failed …

Microglia are specialized brain-resident macrophages that play crucial roles in brain
development, homeostasis, and disease. However, until now, the ability to model …

Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that
are increasingly recognized to be essential players in the development, homeostasis and …

The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia …

Cerebral organoids are 3D stem cell-derived models that can be utilized to study the human
brain. The current consensus is that cerebral organoids consist of cells derived from the …

Aberrant inflammation in the CNS has been implicated as a major player in the
pathogenesis of human neurodegenerative disease. We developed a new approach to …

Microglia are the resident macrophages of the central nervous system. They play key roles
in brain development, and physiology during life and aging. Equipped with a variety of …

Microglia are resident macrophages of the CNS that are involved in its development,
homeostasis and response to infection and damage. Microglial activation is a common …

Bio-integrated devices need power sources to operate,. Despite widely used technologies
that can provide power to large-scale targets, such as wired energy supplies from batteries …