Experimental autoimmune encephalomyelitis (EAE) is the most commonly used
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …

Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of
T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on …

Since the discovery of the cannabinoid receptors and their endogenous ligands, significant
advances have been made in studying the physiological function of the endocannabinoid …

The major psychoactive constituent of Cannabis sativa, Δ 9-tetrahydrocannabinol (Δ 9-THC),
and endogenous cannabinoid ligands, such as anandamide, signal through G-protein …

Interleukins are considered to be key players in the chronic vascular inflammatory response
that is typical of atherosclerosis. Thus, the expression of proinflammatory interleukins and …

The importance of transforming growth factor-beta-1 (TGF-β1) in immunoregulation and
tolerance has been increasingly recognized. It is now proposed that there are populations of …

Interleukin-10 (IL-10) is an immunoregulatory cytokine that plays a crucial role in
inflammatory and immune reactions. It has potent anti-inflammatory and immunosuppressive …

Interleukin-10 (IL-10) is a pleiotropic cytokine that modulates the function of several adaptive
immunity-related cells. Although generally considered an immunosuppressive molecule, IL …

T cells expressing an invariant Vα19-Jα33 T cell receptor α-chain (Vα19i TCR) are restricted
by the nonpolymorphic major histocompatibility complex class Ib molecule MR1. Whether …

The effectiveness of interleukin 10 (IL-10) in the treatment of autoimmune-mediated central
nervous system inflammation is controversial. Studies of the model system, experimental …