The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Tooth enamel, renowned for its high stiffness, hardness, and viscoelasticity, is an ideal
model for designing biomimetic materials, but accurate replication of complex hierarchical …

The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

Although the effects of dehydration on the mechanical behavior of cortical bone are known,
the underlying mechanisms for such effects are not clear. We hypothesize that the …

Tissue engineering may be defined as the application of biological, chemical and
engineering principles toward the repair, restoration or regeneration of living tissue using …

Although the disulfide bond crosslinked hyaluronic acid hydrogels have been reported by
many research groups, the major researches were focused on effectively forming hydrogels …

Bone fractures affect the health of many people and have a significant social and economic
effect. Often, bones fracture due to impacts, sudden falls or trauma. In order to numerically …

Water constitutes roughly a quarter of the cortical bone by volume yet can greatly influence
mechanical properties and tissue quality. There is a growing appreciation for how water can …

Bone regeneration requires scaffolds with a suitable nanostructured 3D-network and
decorated with bioactive functionalities to promote cell ingrowth and induce the intended …