Highlights•IEC invasion is a crucial step in the life cycle of non-typhoidal Salmonella.•TTSS-
1 effectors SopE/E2 and particularly SipA mediate IEC invasion in mice.•Entry structures …

The human non-canonical inflammasome controls caspase-4 activation and gasdermin-D-
dependent pyroptosis in response to cytosolic bacterial lipopolysaccharide (LPS). Since …

Novel biosensors already provide a fast way to detect the adhesion of whole bacteria (or
parts of them), biofilm formation, and the effect of antibiotics. Moreover, the detection …

Within epithelial cells, Pseudomonas aeruginosa depends on its type III secretion system
(T3SS) to escape vacuoles and replicate rapidly in the cytosol. Previously, it was assumed …

Salmonella is a human and animal pathogen that causes gastro-enteric diseases. The key
to Salmonella infection is its entry into intestinal epithelial cells, where the bacterium resides …

The enteric bacterial pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium),
utilizes two type III secretion systems (T3SSs) to invade host cells, survive and replicate …

Salmonella Typhimurium (S. Typhimurium) is an enteric bacterium capable of invading a
wide range of hosts, including rodents and humans. It targets different host cell types …

Intracellular bacterial pathogens gain entry to mammalian cells inside a vacuole derived
from the host membrane. Some of them escape the bacteria-containing vacuole (BCV) and …

Salmonella enterica serovar Typhimurium (S. Tm) infections of cultured cell lines have given
rise to the ruffle model for epithelial cell invasion. According to this model, the Type-Three …

Uptake of large volumes of extracellular fluid by actin-dependent macropinocytosis has an
important role in infection, immunity and cancer development. A key question is how actin …