[HTML][HTML] From structure to function–Ligand recognition by myeloid C-type lectin receptors

S Fischer, F Stegmann, VS Gnanapragassam… - Computational and …, 2022 - Elsevier
The relevance of protein-glycan interactions in immunity has long been underestimated. Yet,
the immune system possesses numerous classes of glycan-binding proteins, so-called …

[PDF][PDF] Microbiome management in the social amoeba Dictyostelium discoideum compared to humans

T Farinholt, C Dinh, A Kuspa - Int J Dev Biol, 2019 - academia.edu
Social amoebae and humans use common strategies to orchestrate their interactions with
the bacteria in their respective environments and within their bodies. These strategies …

Mycobacterium bovis BCG infection alters the macrophage N-glycome

C Delannoy, C Huang, B Coddeville, JY Chen… - Molecular omics, 2020 - pubs.rsc.org
Macrophage glycosylation is essential to initiate the host-immune defense but may also be
targeted by pathogens to promote infection. Indeed, the alteration of the cell-surface …

Self-referential immune recognition through C-type lectin receptors

C Guenther, M Nagae, S Yamasaki - Advances in Immunology, 2022 - Elsevier
The term “lectin” is derived from the Latin word lego-(aggregate)(Boyd & Shapleigh, 1954).
Indeed, lectins' folds can flexibly alter their pocket structures just like Lego blocks, which …

Microbial lectins as a potential therapeutics for the prevention of certain human diseases

S Bektas, E Kaptan - Life Sciences, 2024 - Elsevier
Lectins are protein or glycoprotein molecules with a specific ability to bind to carbohydrates.
From viruses to mammals, they are found in various organisms and exhibit remarkable …

Leguminosae lectins as biological tools in medical research: a review

PPS Barbosa, FN Araújo, JM Almeida… - Brazilian Archives of …, 2021 - SciELO Brasil
Lectins were discovered first in plants and later in other living things, and nowadays it is
known that they are present in almost all many life forms. These proteins can bind to specific …

Long and short-term metformin consumption as a potential therapy to prevent complications of COVID-19

E Shaseb, S Ghaffary, A Garjani… - Advanced …, 2022 - pmc.ncbi.nlm.nih.gov
Purpose: The aim of the study is to evaluate the effect of metformin in complication
improvement of hospitalized patients with COVID-19. Methods: This was a randomized …

Crystal structure of an L‐type lectin domain from archaea

F Khan, S Kaza - Proteins: Structure, Function, and …, 2023 - Wiley Online Library
The crystal structures of an L‐type lectin domain from Methanocaldococcus jannaschii in
apo and mannose‐bound forms have been determined. A thorough investigation of L‐type …

[HTML][HTML] R-Type Lectins

RD Cummings, RL Schnaar, Y Ozeki - Essentials of Glycobiology …, 2022 - ncbi.nlm.nih.gov
The R-type lectin superfamily is characterized by a carbohydrate-recognition domain (CRD)
originally reported in a polypeptide of ricin, a plant toxin. Ricin was the first lectin discovered …

Lectins are the sparkle of Hope for combating coronaviruses and the global COVID-19

HS Abbas, M Kotakonda - Advanced Pharmaceutical Bulletin, 2021 - pmc.ncbi.nlm.nih.gov
Today the crisis of coronavirus disease 2019 (COVID-19) pandemic represents a
threatworldwide because it is a leading cause of human morbidity and mortality. Besides, it …