The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Metallodrugs offer potential for unique mechanisms of drug action based on the choice of
the metal, its oxidation state, the types and number of coordinated ligands and the …

Inflammasomes are high molecular weight complexes that sense and react to injury and
infection. Their activation induces caspase-1 activation and release of interleukin-1β, a pro …

Abstract Nowadays, 4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene–better known as BODIPY
radical dot–is at the forefront of fluorophores for life sciences. Indeed, its high brightness, its …

Over the past few decades, the realm of inorganic medicinal chemistry has been dominated
by the study of the anti-cancer properties of transition metal complexes, particularly those …

In the last few years, metallodrugs play a key role in the development of medicinal chemistry.
The choice of metal ion, its oxidation state and stability, and the choice of inert and labile …

Gold compounds have emerged as a novel class of metallodrugs with a promising future in
medicinal inorganic chemistry. Despite gold compounds have been intensively investigated …

The drugs currently used to treat leishmaniases have limitations concerning cost, efficacy,
and safety, making the search for new therapeutic approaches urgent. We found that the …

The current anticancer and antileishmanial drug arsenal presents several limitations
concerning their specificity, efficacy, costs and the emergence of drug-resistant cells lines …