Click chemistry strategies for the accelerated synthesis of functional macromolecules

Z Geng, JJ Shin, Y Xi, CJ Hawker - Journal of Polymer Science, 2021 - Wiley Online Library
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …

A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

CR Powell, KM Dillon, JB Matson - Biochemical pharmacology, 2018 - Elsevier
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

50th Anniversary Perspective: Polymer Functionalization

E Blasco, MB Sims, AS Goldmann, BS Sumerlin… - …, 2017 - ACS Publications
The translation of small molecule chemistries into efficient methodologies for polymer
functionalization spans several decades, enabling critical advances in soft matter materials …

Glutathione responsive polymers and their application in drug delivery systems

JF Quinn, MR Whittaker, TP Davis - Polymer Chemistry, 2017 - pubs.rsc.org
Materials which respond to biological cues are the subject of intense research interest due
to their possible application in smart drug delivery vehicles. In particular, novel polymers …

Progress and perspective on hydrogen sulfide donors and their biomedical applications

ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

Hydrogen sulfide: an emerging precision strategy for gas therapy

H Ding, J Chang, F He, S Gai… - Advanced Healthcare …, 2022 - Wiley Online Library
Advances in nanotechnology have enabled the rapid development of stimuli‐responsive
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …

Toward hydrogen sulfide based therapeutics: critical drug delivery and developability issues

Y Zheng, B Yu, LK De La Cruz… - Medicinal Research …, 2018 - Wiley Online Library
Abstract Hydrogen sulfide (H2S), together with nitric oxide (NO) and carbon monoxide (CO),
belongs to the gasotransmitter family and plays important roles in mammals as a signaling …

Therapeutic Delivery of H2S via COS: Small Molecule and Polymeric Donors with Benign Byproducts

CR Powell, JC Foster, B Okyere… - Journal of the …, 2016 - ACS Publications
Carbonyl sulfide (COS) is a gas that may play important roles in mammalian and bacterial
biology, but its study is limited by a lack of suitable donor molecules. We report here the use …

Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules

J Hu, Y Fang, X Huang, R Qiao, JF Quinn… - Advanced Drug Delivery …, 2021 - Elsevier
In addition to being notorious air pollutants, nitric oxide (NO), carbon monoxide (CO), and
hydrogen sulfide (H 2 S) have also been known as endogenous gaseous signaling …