The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

Optical sensing of specific molecular targets and pathways deep inside living mice has
become possible as a result of a number of advances. These include design of …

The term molecular imaging can be broadly defined as the in vivo characterization and
measurement of biologic processes at the cellular and molecular level. In contradistinction to …

Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

Quantum dots having four different surface coatings were tested for use in in vivo imaging.
Localization was successfully monitored by fluorescence imaging of living animals, by …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

The development of miniaturized imaging equipment and reporter probes has improved our
ability to study animal models of disease, such as transgenic and knockout mice. These …

Tumour responses to treatment are still largely assessed from imaging measurements of
reductions in tumour size. However, this can take several weeks to become manifest and in …

The deep tissue propagation of near-infrared (NIR) light between 700–900 nm offers new
opportunities for diagnostic imaging when employing sensitive detection techniques and …

Molecular imaging enables the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …