Dietary polyphenols regulate appetite mechanism via gut-brain axis and gut homeostasis

H Liu, X Guo, K Jiang, B Shi, L Liu, R Hou, G Chen… - Food Chemistry, 2024 - Elsevier
Nowadays, due to the rise of fast-food consumption, the metabolic diseases are increasing
as a result of high-sugar and high-fat diets. Therefore, there is an urgent need for natural …

Neuroendocrine gut–brain signaling in obesity

T Gruber, F Lechner, JP Krieger… - Trends in Endocrinology …, 2024 - cell.com
The past decades have witnessed the rise and fall of several, largely unsuccessful,
therapeutic attempts to bring the escalating obesity pandemic to a halt. Looking back to look …

Vagus nerve stimulation (VNS) modulates synaptic plasticity in the infralimbic cortex via Trk-B receptor activation to reduce drug-seeking in male rats

CM Driskill, JE Childs, AJ Phensy… - Journal of …, 2024 - Soc Neuroscience
Drugs of abuse cause changes in the prefrontal cortex (PFC) and associated regions that
impair inhibitory control over drug-seeking. Breaking the contingencies between drug …

[HTML][HTML] Molecular Pharmacology of Vitamin C and Relevance to Health and Obesity—A Narrative Review

RB Wilson, Y Liang, D Kaushal, A Carr - International Journal of …, 2024 - mdpi.com
The role of food constituents as pharmacological agents is an important consideration in
health and obesity. Vitamin C acts as a small molecule antioxidant but is also a co-factor for …

FGF21 as a mediator of adaptive changes in food intake and macronutrient preference in response to protein restriction

SQ Kim, RA Spann, MSH Khan, HR Berthoud… - …, 2024 - Elsevier
Free-feeding animals navigate complex nutritional landscapes in which food availability,
cost, and nutritional value can vary markedly. Animals have thus developed neural …

[HTML][HTML] Diabetes mellitus—Progress and opportunities in the evolving epidemic

ED Abel, AL Gloyn, C Evans-Molina, JJ Joseph… - Cell, 2024 - cell.com
Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …

[HTML][HTML] The gut-brain vagal axis scales hippocampal memory processes and plasticity

O Onimus, F Arrivet, IN de Oliveira Souza… - Neurobiology of …, 2024 - Elsevier
The vagus nerve serves as an interoceptive relay between the body and the brain. Despite
its well-established role in feeding behaviors, energy metabolism, and cognitive functions …

[HTML][HTML] Complex carbohydrate utilization by gut bacteria modulates host food preference

BY Kristie, C Son, A Chandra, J Paramo, A Novoselov… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The gut microbiota interacts directly with dietary nutrients and has the ability to modify host
feeding behavior, but the underlying mechanisms remain poorly understood. Select gut …

Zebrafish: A trending model for gut-brain axis investigation

NS Kiran, C Yashaswini, A Chatterjee - Aquatic Toxicology, 2024 - Elsevier
Zebrafish (Danio rerio) has ascended as a pivotal model organism in the realm of gut-brain
axis research, principally owing to its high-throughput experimental capabilities and …

Soy-Based High-Protein Spheric Foods with the Appearance of Familiar Sugary Snacks

H Yano, R Tanaka, W Fu - Foods, 2024 - mdpi.com
Excessive consumption of sugary foods increases the likelihood of obesity, as well as the
preventable risk of lifestyle illnesses such as diabetes and cardiovascular diseases …