Massive segmental bone defects (SBD) are mostly treated by removing the fibula and
transplanting it complete with blood supply. While revolutionary 50 years ago, this remains …

Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …

目的探讨用抗生素骨水泥治疗糖尿病足溃疡(DFU) 的临床效果及其相关机制.
方法采用前瞻性随机对照研究方法. 2020 年8 月—2022 年8 月, 空军军医大学第一附属医院 …

Osteoblasts and osteoclasts play a crucial role in the dynamically coupled balance during
bone regeneration and remodeling. They complement and restrict each other in the human …

Background The periosteum stem cells (PSCs) plays a critical role in bone regeneration and
defect reconstruction. Insertion of polymethyl methacrylate (PMMA) bone cement can form …

Because of its simplicity, reliability, and replicability, the Masquelet induced membrane
technique (IMT) has become one of the preferred methods for critical bone defect …

During bone regeneration, the periosteum acts as a carrier for key regenerative cues,
delivering osteochondroprogenitor cells and crucial growth factors to the injured bone. We …

Large bone defects resulting from trauma, infection and tumors are usually difficult for the
body's repair mechanisms to heal spontaneously. Generally, various types of bones and …

In bone tissue engineering studies, establishing vascular networks plays a crucial role in
enhancing bone graft repair strategies. While most engineered bones rely on host vascular …

The repair of orthopedic and maxillofacial defects in modern medicine currently relies
heavily on the use of autograft, allograft, void fillers, or other structural material composites …